Institute of Cardiovascular Regeneration Webtool Repository

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                ),
                E_USER_WARNING
            );

$key = 'cake_dev_en-us'
$value = array(
	'LC_MESSAGES' => array()
)
$config = '_cake_core_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/c-it-loci/app/tmp/cache/persistent/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false

Cache::write() - CORE/Cake/Cache/Cache.php, line 323
I18n::translate() - CORE/Cake/I18n/I18n.php, line 237
__d - CORE/Cake/basics.php, line 617
Cache::write() - CORE/Cake/Cache/Cache.php, line 321
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 219
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::query() - CORE/Cake/Model/Model.php, line 3353
PagesController::sharedtissues() - APP/Controller/PagesController.php, line 121
PagesController::display() - APP/Controller/PagesController.php, line 176
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

Warning (512): _cake_model_ cache was unable to write 'default_citloci_list' to File cache [CORE/Cake/Cache/Cache.php, line 323]

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                ),
                E_USER_WARNING
            );

$key = 'default_citloci_list'
$value = null
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/c-it-loci/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false

Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 219
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::query() - CORE/Cake/Model/Model.php, line 3353
PagesController::sharedtissues() - APP/Controller/PagesController.php, line 121
PagesController::display() - APP/Controller/PagesController.php, line 176
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

Warning (512): _cake_model_ cache was unable to write 'default_citloci_list' to File cache [CORE/Cake/Cache/Cache.php, line 323]

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                ),
                E_USER_WARNING
            );

$key = 'default_citloci_list'
$value = array(
	(int) 0 => 'conserved_region_elements',
	(int) 1 => 'conserved_regions',
	(int) 2 => 'diffexp',
	(int) 3 => 'experiment',
	(int) 4 => 'expressed_transcripts',
	(int) 5 => 'external_accessions',
	(int) 6 => 'genes',
	(int) 7 => 'go_annotations',
	(int) 8 => 'homologues',
	(int) 9 => 'maptranscripttoregion',
	(int) 10 => 'organism',
	(int) 11 => 'sample',
	(int) 12 => 'study',
	(int) 13 => 'synonyms',
	(int) 14 => 'transcripts'
)
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/c-it-loci/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false

Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 236
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::query() - CORE/Cake/Model/Model.php, line 3353
PagesController::sharedtissues() - APP/Controller/PagesController.php, line 121
PagesController::display() - APP/Controller/PagesController.php, line 176
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

C-It-Loci is a tool to explore and to compare the expression profiles of conserved loci among various tissues in three organisms. Conversed loci are pairs of adjacent homologous protein-coding genes shared between one or more species. Expression profiles are based on RNA-seq data from many sources to derive tissue enrichment or specificity. Classifications of transcripts are based on the latest release of ENSEMBL, which will be updated in a timely manner. In addition to protein-coding genes, expression profiles of yet-to-be-characterized long non-coding RNAs (lncRNAs) are included. To define species-conservation of lncRNAs, we introduced the concept called "positional conservation" on top of "sequence conservation", which is the most common way to find homologous lncRNAs among species. We anticipate that C-It-Loci will be a valuable tool to perform in silico screening of tissue-enriched lncRNAs to be studied further by biological experiments.

Quick Search: Select a tissue and expression type for a quick overview.

Warning (512): _cake_core_ cache was unable to write 'file_map' to File cache [CORE/Cake/Cache/Cache.php, line 323]

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                ),
                E_USER_WARNING
            );

$key = 'file_map'
$value = array(
	'Configure' => '/var/www/c-it-loci/lib/Cake/Core/Configure.php',
	'Hash' => '/var/www/c-it-loci/lib/Cake/Utility/Hash.php',
	'Cache' => '/var/www/c-it-loci/lib/Cake/Cache/Cache.php',
	'FileEngine' => '/var/www/c-it-loci/lib/Cake/Cache/Engine/FileEngine.php',
	'CacheEngine' => '/var/www/c-it-loci/lib/Cake/Cache/CacheEngine.php',
	'Inflector' => '/var/www/c-it-loci/lib/Cake/Utility/Inflector.php',
	'ErrorHandler' => '/var/www/c-it-loci/lib/Cake/Error/ErrorHandler.php',
	'CakePlugin' => '/var/www/c-it-loci/lib/Cake/Core/CakePlugin.php',
	'CakeLog' => '/var/www/c-it-loci/lib/Cake/Log/CakeLog.php',
	'LogEngineCollection' => '/var/www/c-it-loci/lib/Cake/Log/LogEngineCollection.php',
	'ObjectCollection' => '/var/www/c-it-loci/lib/Cake/Utility/ObjectCollection.php',
	'FileLog' => '/var/www/c-it-loci/lib/Cake/Log/Engine/FileLog.php',
	'BaseLog' => '/var/www/c-it-loci/lib/Cake/Log/Engine/BaseLog.php',
	'CakeLogInterface' => '/var/www/c-it-loci/lib/Cake/Log/CakeLogInterface.php',
	'Debugger' => '/var/www/c-it-loci/lib/Cake/Utility/Debugger.php',
	'String' => '/var/www/c-it-loci/lib/Cake/Utility/String.php',
	'Dispatcher' => '/var/www/c-it-loci/lib/Cake/Routing/Dispatcher.php',
	'CakeEventListener' => '/var/www/c-it-loci/lib/Cake/Event/CakeEventListener.php',
	'CakeRequest' => '/var/www/c-it-loci/lib/Cake/Network/CakeRequest.php',
	'CakeResponse' => '/var/www/c-it-loci/lib/Cake/Network/CakeResponse.php',
	'CakeEvent' => '/var/www/c-it-loci/lib/Cake/Event/CakeEvent.php',
	'CakeEventManager' => '/var/www/c-it-loci/lib/Cake/Event/CakeEventManager.php',
	'AssetDispatcher' => '/var/www/c-it-loci/lib/Cake/Routing/Filter/AssetDispatcher.php',
	'DispatcherFilter' => '/var/www/c-it-loci/lib/Cake/Routing/DispatcherFilter.php',
	'CacheDispatcher' => '/var/www/c-it-loci/lib/Cake/Routing/Filter/CacheDispatcher.php',
	'Router' => '/var/www/c-it-loci/lib/Cake/Routing/Router.php',
	'CakeRoute' => '/var/www/c-it-loci/lib/Cake/Routing/Route/CakeRoute.php',
	'PluginShortRoute' => '/var/www/c-it-loci/lib/Cake/Routing/Route/PluginShortRoute.php',
	'PagesController' => '/var/www/c-it-loci/app/Controller/PagesController.php',
	'AppController' => '/var/www/c-it-loci/app/Controller/AppController.php',
	'Controller' => '/var/www/c-it-loci/lib/Cake/Controller/Controller.php',
	'Object' => '/var/www/c-it-loci/lib/Cake/Core/Object.php',
	'ComponentCollection' => '/var/www/c-it-loci/lib/Cake/Controller/ComponentCollection.php',
	'SessionComponent' => '/var/www/c-it-loci/lib/Cake/Controller/Component/SessionComponent.php',
	'Component' => '/var/www/c-it-loci/lib/Cake/Controller/Component.php',
	'ClassRegistry' => '/var/www/c-it-loci/lib/Cake/Utility/ClassRegistry.php',
	'Page' => '/var/www/c-it-loci/app/Model/Page.php',
	'AppModel' => '/var/www/c-it-loci/app/Model/AppModel.php',
	'Model' => '/var/www/c-it-loci/lib/Cake/Model/Model.php',
	'BehaviorCollection' => '/var/www/c-it-loci/lib/Cake/Model/BehaviorCollection.php',
	'ConnectionManager' => '/var/www/c-it-loci/lib/Cake/Model/ConnectionManager.php',
	'Mysql' => '/var/www/c-it-loci/lib/Cake/Model/Datasource/Database/Mysql.php',
	'DboSource' => '/var/www/c-it-loci/lib/Cake/Model/Datasource/DboSource.php',
	'DataSource' => '/var/www/c-it-loci/lib/Cake/Model/Datasource/DataSource.php',
	'I18n' => '/var/www/c-it-loci/lib/Cake/I18n/I18n.php',
	'L10n' => '/var/www/c-it-loci/lib/Cake/I18n/L10n.php',
	'CakeSession' => '/var/www/c-it-loci/lib/Cake/Model/Datasource/CakeSession.php',
	'Set' => '/var/www/c-it-loci/lib/Cake/Utility/Set.php',
	'View' => '/var/www/c-it-loci/lib/Cake/View/View.php',
	'HelperCollection' => '/var/www/c-it-loci/lib/Cake/View/HelperCollection.php',
	'ViewBlock' => '/var/www/c-it-loci/lib/Cake/View/ViewBlock.php',
	'FormHelper' => '/var/www/c-it-loci/lib/Cake/View/Helper/FormHelper.php',
	'AppHelper' => '/var/www/c-it-loci/app/View/Helper/AppHelper.php',
	'Helper' => '/var/www/c-it-loci/lib/Cake/View/Helper.php',
	'HtmlHelper' => '/var/www/c-it-loci/lib/Cake/View/Helper/HtmlHelper.php',
	'SessionHelper' => '/var/www/c-it-loci/lib/Cake/View/Helper/SessionHelper.php'
)
$config = '_cake_core_'
$settings = array(
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	'engine' => 'File',
	'path' => '/var/www/c-it-loci/app/tmp/cache/persistent/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false

Cache::write() - CORE/Cake/Cache/Cache.php, line 323
App::shutdown() - CORE/Cake/Core/App.php, line 899
[main] - [internal], line ??

Warning (512): _cake_core_ cache was unable to write 'method_cache' to File cache [CORE/Cake/Cache/Cache.php, line 323]

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                ),
                E_USER_WARNING
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	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/c-it-loci/app/tmp/cache/persistent/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false

Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DboSource::__destruct() - CORE/Cake/Model/Datasource/DboSource.php, line 3539
[main] - [internal], line ??

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Quick Search: Select a tissue and expression type for a quick overview.

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