C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nerve growth factor receptor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000064300 NGFR 9606 + 17:49495293-49515017 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000172229 NGFR-001 49495293-49515017 protein_coding
  ENST00000504201 NGFR-002 49497391-49513372 protein_coding
  ENST00000509200 NGFR-003 49496624-49506385 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000172229ENST00000504201
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000172229 9.017±0.00 47.067±0.00 0.209±0.00 0.966±0.84 4.729±3.29 5.667±5.60 3.077±2.66 4.459±2.28 3.236±2.02 2.095±1.62 0.721±0.00 2.906±3.03 25.943±4.10 4.321±0.00
ENST00000504201 N/A N/A 0.217±0.00 0.063±0.00 N/A N/A N/A N/A N/A N/A 0.045±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000877 CIL_000877_0001 VISTA 17:49438854-50041456
CIL_0009BV CIL_0009BV_0001 VISTA 17:49438877-50041441
CIL_0007QJ CIL_0007QJ_0001 VISTA 17:49459872-50061823
CIL_0004N4 CIL_0004N4_0002 CGP 17:49495293-49583827

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004871 TAS signal transducer activity
GO:0004872 TAS receptor activity
GO:0004888 TAS transmembrane signaling receptor activity
GO:0005035 IEA death receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005576 TAS extracellular region
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0005768 TAS endosome
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006886 ISS intracellular protein transport
GO:0007165 IEA signal transduction
GO:0007411 IEA axon guidance
GO:0007417 IEA central nervous system development
GO:0009986 ISS cell surface
GO:0010468 IEA regulation of gene expression
GO:0012501 IEA programmed cell death
GO:0016048 IEA detection of temperature stimulus
GO:0017137 ISS Rab GTPase binding
GO:0021675 IEA nerve development
GO:0031069 IEA hair follicle morphogenesis
GO:0031293 TAS membrane protein intracellular domain proteolysis
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032922 ISS circadian regulation of gene expression
GO:0040037 IEA negative regulation of fibroblast growth factor receptor signaling pathway
GO:0042488 IEA positive regulation of odontogenesis of dentin-containing tooth
GO:0042593 ISS glucose homeostasis
GO:0043065 TAS positive regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0043281 TAS regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043588 IEA skin development
GO:0045786 TAS negative regulation of cell cycle
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048146 IEA positive regulation of fibroblast proliferation
GO:0048406 IEA nerve growth factor binding
GO:0050770 TAS regulation of axonogenesis
GO:0050771 TAS negative regulation of axonogenesis
GO:0050772 TAS positive regulation of axonogenesis
GO:0051799 IEA negative regulation of hair follicle development
GO:0097190 TAS apoptotic signaling pathway
GO:0097481 IEA neuronal postsynaptic density
GO:2001235 IEA positive regulation of apoptotic signaling pathway
GO:2001273 ISS regulation of glucose import in response to insulin stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000032984 ngfrb nerve growth factor receptor b protein_coding Danio_rerio
ENSDARG00000088708 NGFR (2 of 3) nerve growth factor receptor protein_coding Danio_rerio
ENSDARG00000089223 ngfrb nerve growth factor receptor b protein_coding Danio_rerio
ENSMUSG00000000120 Ngfr nerve growth factor receptor (TNFR superfamily, member 16) protein_coding Mus_musculus

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