C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hyaluronoglucosaminidase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000068001 HYAL2 9606 - 3:50317790-50322906 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000357750 HYAL2-001 50317796-50322906 protein_coding
  ENST00000395139 HYAL2-002 50317809-50321713 protein_coding
  ENST00000415028 HYAL2-009 50320347-50321149 protein_coding
  ENST00000424190 HYAL2-008 50320137-50320987 protein_coding
  ENST00000426286 HYAL2-010 50320246-50320948 protein_coding
  ENST00000428028 HYAL2-006 50320260-50322741 protein_coding
  ENST00000442581 HYAL2-004 50317812-50322777 protein_coding
  ENST00000447092 HYAL2-003 50317790-50322782 protein_coding
  ENST00000458018 HYAL2-007 50320127-50321217 protein_coding
  ENST00000481597 HYAL2-005 50318589-50322741 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000357750ENST00000395139ENST00000442581ENST00000447092ENST00000481597
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000357750 32.440±0.00 42.750±0.00 N/A 4.197±0.00 4.852±0.00 2.715±1.26 5.539±3.12 1.966±0.00 4.345±0.00 17.694±3.93 N/A 9.967±3.90 76.343±17.74 N/A
ENST00000395139 13.171±0.00 64.950±0.00 N/A 5.175±2.77 10.854±0.00 4.417±0.00 8.730±7.86 12.199±10.58 22.913±0.00 48.835±0.00 6.734±2.33 9.728±4.13 35.276±10.90 13.496±0.00
ENST00000442581 N/A N/A N/A N/A N/A 3.882±0.00 N/A 14.947±0.00 N/A 19.245±0.00 N/A N/A N/A N/A
ENST00000447092 N/A N/A N/A N/A N/A N/A N/A 0.621±0.00 N/A N/A N/A N/A N/A N/A
ENST00000481597 N/A N/A 3.506±0.00 N/A 5.261±0.00 N/A N/A N/A 3.496±0.00 11.757±0.00 N/A 3.193±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008D8 CIL_0008D8_0001 VISTA 3:50299047-50902727
CIL_0003FI CIL_0003FI_0002 CGP 3:50317790-50328251

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 ISS Golgi membrane
GO:0000302 IDA response to reactive oxygen species
GO:0001618 IDA virus receptor activity
GO:0001822 ISS kidney development
GO:0002244 IEA hematopoietic progenitor cell differentiation
GO:0004415 IEA:IDA hyalurononglucosaminidase activity
GO:0005515 IPI protein binding
GO:0005540 IDA hyaluronic acid binding
GO:0005737 IDA cytoplasm
GO:0005764 IDA lysosome
GO:0005783 NAS endoplasmic reticulum
GO:0005829 IDA cytosol
GO:0005886 TAS plasma membrane
GO:0005902 IDA microvillus
GO:0005975 IEA:TAS carbohydrate metabolic process
GO:0006027 IDA glycosaminoglycan catabolic process
GO:0009615 IDA response to virus
GO:0009986 ISS cell surface
GO:0010259 IEA multicellular organismal aging
GO:0010764 IDA negative regulation of fibroblast migration
GO:0016023 IDA cytoplasmic membrane-bounded vesicle
GO:0016324 IDA apical plasma membrane
GO:0019064 IDA fusion of virus membrane with host plasma membrane
GO:0019087 ISS transformation of host cell by virus
GO:0019899 IPI enzyme binding
GO:0030139 IDA endocytic vesicle
GO:0030203 TAS glycosaminoglycan metabolic process
GO:0030212 TAS hyaluronan metabolic process
GO:0030214 IDA hyaluronan catabolic process
GO:0030294 IDA receptor signaling protein tyrosine kinase inhibitor activity
GO:0030308 IDA negative regulation of cell growth
GO:0030971 IPI receptor tyrosine kinase binding
GO:0031362 IDA anchored component of external side of plasma membrane
GO:0031410 IDA cytoplasmic vesicle
GO:0033906 IDA hyaluronoglucuronidase activity
GO:0035810 ISS positive regulation of urine volume
GO:0042117 IDA monocyte activation
GO:0042307 ISS positive regulation of protein import into nucleus
GO:0043407 IDA negative regulation of MAP kinase activity
GO:0044281 TAS small molecule metabolic process
GO:0044344 IDA cellular response to fibroblast growth factor stimulus
GO:0045121 IDA membrane raft
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0046658 IDA anchored component of plasma membrane
GO:0046677 IEP response to antibiotic
GO:0046718 ISS viral entry into host cell
GO:0048471 IDA perinuclear region of cytoplasm
GO:0048705 IEA skeletal system morphogenesis
GO:0050431 ISS transforming growth factor beta binding
GO:0050729 IDA positive regulation of inflammatory response
GO:0051216 IEP cartilage development
GO:0051607 IEA defense response to virus
GO:0051898 IDA negative regulation of protein kinase B signaling
GO:0060586 IEA multicellular organismal iron ion homeostasis
GO:0061099 IDA negative regulation of protein tyrosine kinase activity
GO:0070295 ISS renal water absorption
GO:0071347 IDA cellular response to interleukin-1
GO:0071356 IEP cellular response to tumor necrosis factor
GO:0071493 IDA cellular response to UV-B
GO:0071560 IDA cellular response to transforming growth factor beta stimulus
GO:2000484 IDA positive regulation of interleukin-8 secretion
GO:2000778 IDA positive regulation of interleukin-6 secretion
GO:2001238 ISS positive regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059931 HYAL2 (1 of 3) hyaluronoglucosaminidase 2 protein_coding Danio_rerio
ENSDARG00000062997 hyal2 hyaluronoglucosaminidase 2 protein_coding Danio_rerio
ENSDARG00000077421 HYAL2 (3 of 3) hyaluronoglucosaminidase 2 protein_coding Danio_rerio
ENSMUSG00000010047 Hyal2 hyaluronoglucosaminidase 2 protein_coding Mus_musculus

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