C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ring-box 1, E3 ubiquitin protein ligase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100387 RBX1 9606 + 22:40951347-40973309 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000216225 RBX1-001 40951359-40973309 protein_coding
  ENST00000467617 RBX1-002 40966201-40972662 retained_intron
  ENST00000476110 RBX1-003 40951347-40964411 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000216225ENST00000467617ENST00000476110
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000216225 19.593±0.00 32.897±0.00 0.318±0.00 16.365±10.20 23.947±0.00 8.670±7.78 10.911±10.00 14.893±11.29 9.346±6.66 16.961±15.06 7.818±5.04 13.516±8.55 26.904±11.68 20.396±14.02
ENST00000467617 N/A N/A 0.148±0.00 N/A 0.942±0.00 0.428±0.00 N/A N/A N/A N/A N/A 1.277±0.00 N/A 1.581±0.00
ENST00000476110 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 13.428±0.00 5.702±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00065L CIL_00065L_0001 CGP 22:40859549-40973309

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005654 TAS nucleoplasm
GO:0005829 ISS cytosol
GO:0006281 IEA DNA repair
GO:0006513 IDA protein monoubiquitination
GO:0007219 TAS Notch signaling pathway
GO:0008270 IEA zinc ion binding
GO:0016032 TAS viral process
GO:0016567 IDA protein ubiquitination
GO:0019005 ISS SCF ubiquitin ligase complex
GO:0019788 IDA NEDD8 ligase activity
GO:0030163 IEA protein catabolic process
GO:0030891 IEA VCB complex
GO:0031146 ISS SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031461 IDA cullin-RING ubiquitin ligase complex
GO:0031462 IDA Cul2-RING ubiquitin ligase complex
GO:0031463 IDA Cul3-RING ubiquitin ligase complex
GO:0031464 IDA Cul4A-RING E3 ubiquitin ligase complex
GO:0031465 IDA Cul4B-RING E3 ubiquitin ligase complex
GO:0031466 IDA Cul5-RING ubiquitin ligase complex
GO:0031467 IDA Cul7-RING ubiquitin ligase complex
GO:0031625 IDA ubiquitin protein ligase binding
GO:0032403 IEA protein complex binding
GO:0043161 IDA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045116 IDA protein neddylation
GO:0061418 TAS regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0071456 TAS cellular response to hypoxia

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038030 rbx1 ring-box 1, E3 ubiquitin protein ligase protein_coding Danio_rerio
ENSMUSG00000022400 Rbx1 ring-box 1 protein_coding Mus_musculus

Loading