C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: WW and C2 domain containing 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000113645 WWC1 9606 + 5:168291651-168472303 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265293 WWC1-001 168291651-168472303 protein_coding
  ENST00000393895 WWC1-004 168371421-168469756 protein_coding
  ENST00000517425 WWC1-012 168406273-168422048 processed_transcript
  ENST00000517646 WWC1-013 168408585-168414488 processed_transcript
  ENST00000518204 WWC1-017 168467693-168469221 retained_intron
  ENST00000518334 WWC1-014 168414130-168423592 retained_intron
  ENST00000519659 WWC1-011 168406258-168410180 retained_intron
  ENST00000519859 WWC1-010 168316620-168397786 processed_transcript
  ENST00000521089 WWC1-002 168292150-168469216 protein_coding
  ENST00000521391 WWC1-016 168464928-168472303 processed_transcript
  ENST00000522140 WWC1-008 168431364-168467888 processed_transcript
  ENST00000523043 WWC1-009 168292246-168408608 processed_transcript
  ENST00000524038 WWC1-007 168430159-168469759 protein_coding
  ENST00000524093 WWC1-015 168428705-168454001 processed_transcript
  ENST00000524228 WWC1-006 168406279-168469757 protein_coding
  ENST00000619752 WWC1-201 168431364-168467888 protein_coding
  ENST00000624315 WWC1-018 168414072-168416522 TEC

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000265293ENST00000393895ENST00000518204ENST00000519659ENST00000521089ENST00000522140ENST00000523043ENST00000524038ENST00000524228
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000265293 0.039±0.00 N/A 1.713±0.00 0.299±0.00 0.486±0.27 N/A 0.028±0.00 4.300±0.00 0.452±0.00 1.732±0.00 0.018±0.00 0.895±0.00 1.108±0.49 0.469±0.00
ENST00000393895 N/A 0.317±0.00 N/A 2.016±1.19 N/A 0.627±0.45 N/A 10.426±0.00 1.769±0.00 N/A N/A N/A 1.475±0.00 0.459±0.00
ENST00000518204 N/A N/A N/A N/A N/A N/A 0.329±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000519659 N/A N/A N/A N/A N/A N/A 0.414±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000521089 N/A N/A 4.206±0.00 3.913±2.68 1.033±0.10 N/A N/A 0.956±0.00 0.217±0.00 5.055±3.14 N/A 1.216±0.52 1.996±0.44 0.595±0.24
ENST00000522140 0.202±0.00 N/A N/A N/A N/A N/A 0.115±0.00 N/A N/A N/A N/A N/A N/A 0.682±0.00
ENST00000523043 0.384±0.00 N/A 10.366±0.00 7.049±0.00 2.596±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000524038 N/A N/A N/A 2.732±1.99 0.947±0.57 0.200±0.00 0.099±0.00 7.981±7.09 2.712±0.00 1.032±0.00 N/A 1.684±0.88 2.991±0.32 0.956±0.00
ENST00000524228 N/A 0.730±0.00 1.405±0.00 2.241±0.00 0.784±0.51 0.164±0.00 0.054±0.01 6.869±6.27 0.942±0.53 6.619±0.00 N/A 1.341±0.59 2.193±0.80 0.255±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0003713 IDA transcription coactivator activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0016477 IDA cell migration
GO:0019900 IPI kinase binding
GO:0030010 TAS establishment of cell polarity
GO:0030674 IEA protein binding, bridging
GO:0032386 TAS regulation of intracellular transport
GO:0032587 IDA ruffle membrane
GO:0032947 IDA protein complex scaffold
GO:0035329 TAS hippo signaling
GO:0035330 IMP regulation of hippo signaling
GO:0035331 IDA negative regulation of hippo signaling
GO:0043234 IEA protein complex
GO:0043410 IDA positive regulation of MAPK cascade
GO:0046621 IMP negative regulation of organ growth
GO:0048471 IDA perinuclear region of cytoplasm

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076041 WWC1 WW and C2 domain containing 1 protein_coding Danio_rerio
ENSMUSG00000018849 Wwc1 WW, C2 and coiled-coil domain containing 1 protein_coding Mus_musculus

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