C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: establishment of sister chromatid cohesion N-acetyltransferase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000171320 ESCO2 9606 + 8:27771949-27812640 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000305188 ESCO2-001 27774386-27805316 protein_coding
  ENST00000397418 ESCO2-201 27774541-27808228 protein_coding
  ENST00000518262 ESCO2-006 27780199-27799601 protein_coding
  ENST00000519637 ESCO2-005 27774669-27776707 protein_coding
  ENST00000522378 ESCO2-002 27774554-27812640 nonsense_mediated_decay
  ENST00000523566 ESCO2-004 27771949-27776870 protein_coding
  ENST00000523910 ESCO2-007 27776510-27780204 processed_transcript
  ENST00000524293 ESCO2-003 27775497-27780095 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000305188ENST00000397418ENST00000518262ENST00000522378ENST00000523910ENST00000524293
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000305188 N/A 0.023±0.00 N/A N/A N/A 0.285±0.00 0.053±0.00 N/A N/A 0.043±0.00 N/A 0.405±0.28 0.148±0.00 2.102±0.70
ENST00000397418 N/A N/A N/A N/A N/A 1.342±0.00 N/A N/A N/A 0.194±0.00 N/A 1.051±0.41 0.145±0.04 1.641±0.00
ENST00000518262 N/A N/A 0.450±0.00 0.535±0.00 0.620±0.44 4.021±0.00 N/A N/A 1.119±0.00 1.002±0.84 N/A N/A N/A N/A
ENST00000522378 0.081±0.00 0.099±0.00 N/A 0.040±0.00 N/A N/A 0.035±0.01 0.112±0.06 N/A 0.075±0.00 0.004±0.00 0.073±0.00 N/A 1.575±0.00
ENST00000523910 N/A N/A N/A N/A 0.654±0.00 N/A 0.084±0.00 N/A N/A 0.274±0.00 N/A 3.419±0.00 0.512±0.33 N/A
ENST00000524293 0.052±0.00 0.080±0.00 N/A 0.009±0.00 0.026±0.00 0.049±0.00 0.013±0.00 0.055±0.00 N/A 0.022±0.00 N/A 0.009±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009DK CIL_0009DK_0001 VISTA 8:27594923-28195834
CIL_0005SU CIL_0005SU_0002 CGP 8:27733311-27812640
CIL_00073A CIL_00073A_0002 CGP 8:27771949-27838095

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000278 TAS mitotic cell cycle
GO:0000785 IDA chromatin
GO:0001741 IEA XY body
GO:0002244 IEA hematopoietic progenitor cell differentiation
GO:0004468 IEA lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005794 IDA Golgi apparatus
GO:0006275 IMP regulation of DNA replication
GO:0006302 IEA double-strand break repair
GO:0007059 IEA chromosome segregation
GO:0010369 IEA chromocenter
GO:0031618 IEA nuclear pericentric heterochromatin
GO:0034421 IMP post-translational protein acetylation
GO:0035861 IEA site of double-strand break
GO:0046872 IEA metal ion binding
GO:0071168 IEA protein localization to chromatin

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014685 esco2 establishment of cohesion 1 homolog 2 protein_coding Danio_rerio
ENSMUSG00000022034 Esco2 establishment of cohesion 1 homolog 2 (S. cerevisiae) protein_coding Mus_musculus

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