C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: splicing factor 3b, subunit 3, 130kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000189091 SF3B3 9606 + 16:70523788-70577670 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000302516 SF3B3-001 70523788-70577668 protein_coding
  ENST00000562722 SF3B3-011 70563729-70565720 retained_intron
  ENST00000562874 SF3B3-020 70576301-70577670 processed_transcript
  ENST00000563739 SF3B3-010 70561349-70567541 retained_intron
  ENST00000564899 SF3B3-004 70524550-70526669 protein_coding
  ENST00000565990 SF3B3-014 70569915-70572299 retained_intron
  ENST00000566095 SF3B3-003 70523791-70528893 protein_coding
  ENST00000567250 SF3B3-008 70550203-70557029 retained_intron
  ENST00000567635 SF3B3-007 70541739-70556206 nonsense_mediated_decay
  ENST00000567654 SF3B3-006 70523893-70529170 protein_coding
  ENST00000568291 SF3B3-009 70554106-70556597 retained_intron
  ENST00000568539 SF3B3-012 70560350-70564033 retained_intron
  ENST00000569687 SF3B3-005 70526901-70529091 protein_coding
  ENST00000572365 SF3B3-016 70538395-70548512 retained_intron
  ENST00000577085 SF3B3-018 70523813-70529018 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000302516ENST00000563739ENST00000565990ENST00000567250ENST00000567635ENST00000568539ENST00000572365
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000302516 1.520±0.00 2.973±0.00 1.244±0.00 6.570±0.00 3.393±1.10 4.027±0.00 2.015±0.82 3.451±1.67 1.707±0.27 2.257±0.99 6.130±0.00 4.525±3.00 4.717±3.81 2.949±1.23
ENST00000563739 N/A N/A 4.572±0.00 8.883±0.00 11.412±1.05 11.409±1.65 10.779±0.00 11.010±2.38 5.934±0.00 12.711±0.00 17.865±0.00 17.584±0.00 17.196±0.00 N/A
ENST00000565990 20.163±0.00 25.510±0.00 N/A N/A 17.378±0.00 21.949±0.00 17.192±0.00 24.122±0.00 14.808±0.00 27.102±0.00 18.762±14.08 37.452±20.81 18.141±3.13 19.164±0.00
ENST00000567250 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 10.441±0.00 14.286±0.00 N/A
ENST00000567635 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 23.213±0.00 21.755±0.00 N/A
ENST00000568539 N/A N/A 20.055±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000572365 N/A N/A 14.236±0.00 N/A N/A N/A 12.373±0.00 N/A N/A 21.025±0.00 15.985±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000375 TAS RNA splicing, via transesterification reactions
GO:0000398 IC mRNA splicing, via spliceosome
GO:0003676 IEA nucleic acid binding
GO:0005515 IPI:IEA protein binding
GO:0005634 IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005681 TAS spliceosomal complex
GO:0005689 IDA U12-type spliceosomal complex
GO:0006397 TAS mRNA processing
GO:0006461 TAS protein complex assembly
GO:0008380 TAS RNA splicing
GO:0010467 TAS gene expression
GO:0030532 TAS small nuclear ribonucleoprotein complex
GO:0071013 IDA catalytic step 2 spliceosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000089880 sf3b3 splicing factor 3b, subunit 3 protein_coding Danio_rerio
ENSMUSG00000033732 Sf3b3 splicing factor 3b, subunit 3 protein_coding Mus_musculus

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