C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: signal-regulatory protein alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000198053 SIRPA 9606 + 20:1894167-1940592 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000356025 SIRPA-002 1894783-1939897 protein_coding
  ENST00000358771 SIRPA-001 1895296-1939897 protein_coding
  ENST00000400068 SIRPA-201 1894167-1939894 protein_coding
  ENST00000622179 SIRPA-003 1894508-1940592 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000356025ENST00000358771ENST00000400068ENST00000622179
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000356025 10.394±0.00 20.145±0.00 1.208±0.00 31.101±20.16 8.849±6.09 5.709±4.26 1.368±0.69 7.569±4.50 14.667±0.00 0.609±0.00 1.171±0.00 8.180±5.14 12.869±2.46 5.089±3.31
ENST00000358771 N/A N/A N/A 6.528±2.25 2.317±0.00 2.487±0.00 N/A 2.642±0.00 1.091±0.00 N/A N/A N/A N/A N/A
ENST00000400068 N/A N/A N/A N/A 1.326±0.00 N/A N/A N/A N/A 2.470±1.81 N/A 1.433±0.00 1.907±0.00 1.954±0.37
ENST00000622179 N/A N/A N/A 5.572±3.05 1.837±0.00 1.270±0.00 N/A N/A 2.026±0.00 N/A N/A 3.577±0.00 N/A 0.958±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005H7 CIL_0005H7_0001 CGP 20:1629152-1940592
CIL_0005HA CIL_0005HA_0001 CGP 20:1894167-1994285

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0007155 TAS cell adhesion
GO:0007596 TAS blood coagulation
GO:0016020 TAS membrane
GO:0016021 IEA integral component of membrane
GO:0017124 IEA SH3 domain binding
GO:0050900 TAS leukocyte migration
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000037902 Sirpa signal-regulatory protein alpha protein_coding Mus_musculus
ENSMUSG00000074677 Sirpb1c signal-regulatory protein beta 1C protein_coding Mus_musculus
ENSMUSG00000095028 Sirpb1b signal-regulatory protein beta 1B protein_coding Mus_musculus
ENSMUSG00000095788 Sirpb1a signal-regulatory protein beta 1A protein_coding Mus_musculus

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