C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: WW, C2 and coiled-coil domain containing 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000018849 Wwc1 10090 - 11:35838400-35980527 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000018993 Wwc1-001 35838400-35980527 protein_coding
  ENSMUST00000127086 Wwc1-003 35868745-35875712 processed_transcript
  ENSMUST00000131001 Wwc1-002 35852195-35853554 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000018993ENSMUST00000127086ENSMUST00000131001
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000018993 2.422±2.42 15.492±2.24 13.193±1.86 16.987±14.23 2.966±1.17 8.187±2.03 0.346±0.15 39.877±10.00 8.367±5.71 52.551±3.03 0.024±0.01 7.881±2.77 26.644±25.63 0.712±0.50
ENSMUST00000127086 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.067±0.01 N/A N/A N/A
ENSMUST00000131001 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.139±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0003713 IEA transcription coactivator activity
GO:0005634 ISS nucleus
GO:0005737 IDA cytoplasm
GO:0005829 IEA cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0016477 ISS cell migration
GO:0019900 IEA kinase binding
GO:0030674 IEA protein binding, bridging
GO:0032587 ISS ruffle membrane
GO:0032947 IEA protein complex scaffold
GO:0035330 IEA regulation of hippo signaling
GO:0035331 IEA negative regulation of hippo signaling
GO:0043234 IEA protein complex
GO:0043410 ISS positive regulation of MAPK cascade
GO:0046621 IEA negative regulation of organ growth
GO:0048471 IEA perinuclear region of cytoplasm

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076041 WWC1 WW and C2 domain containing 1 protein_coding Danio_rerio
ENSG00000113645 WWC1 WW and C2 domain containing 1 protein_coding Homo_sapiens

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