C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mitogen-activated protein kinase kinase kinase 12
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000023050 Map3k12 10090 - 15:102497649-102517064 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023812 Map3k12-002 102497649-102516836 protein_coding
  ENSMUST00000164343 Map3k12-004 102506118-102516812 processed_transcript
  ENSMUST00000165174 Map3k12-005 102505432-102516975 protein_coding
  ENSMUST00000167677 Map3k12-007 102509112-102510792 processed_transcript
  ENSMUST00000169162 Map3k12-008 102505469-102516816 protein_coding
  ENSMUST00000169367 Map3k12-006 102505370-102517004 protein_coding
  ENSMUST00000169377 Map3k12-001 102499025-102517064 protein_coding
  ENSMUST00000171565 Map3k12-003 102498776-102510700 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023812ENSMUST00000169377
Transcript ID Adipose Adrenal Bladder Brain Breast Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023812 7.637±2.15 8.267±0.02 10.243±1.58 17.580±5.23 6.860±0.97 3.702±0.22 6.380±0.15 6.979±1.81 6.282±0.35 3.665±0.85 9.465±1.69 7.596±3.74 3.710±0.00
ENSMUST00000169377 N/A N/A N/A 11.151±2.72 N/A N/A N/A N/A N/A N/A 7.633±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009B4 CIL_0009B4_0002 VISTA 15:102394217-102994945
CIL_00033G CIL_00033G_0003 CGP 15:102470632-102517064

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000186 IEA activation of MAPKK activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004709 IEA MAP kinase kinase kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005829 IDA cytosol
GO:0005886 IDA plasma membrane
GO:0006468 IDA protein phosphorylation
GO:0007254 IEA JNK cascade
GO:0016572 IDA histone phosphorylation
GO:0018105 IDA peptidyl-serine phosphorylation
GO:0018107 IDA peptidyl-threonine phosphorylation
GO:0019901 IEA protein kinase binding
GO:0030424 IDA axon
GO:0030426 IDA growth cone
GO:0042803 IDA protein homodimerization activity
GO:0046777 IDA protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042565 MAP3K12 mitogen-activated protein kinase kinase kinase 12 (map3k12), mRNA protein_coding Danio_rerio
ENSG00000139625 MAP3K12 mitogen-activated protein kinase kinase kinase 12 protein_coding Homo_sapiens

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