C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tumor necrosis factor receptor superfamily, member 1b
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028599 Tnfrsf1b 10090 - 4:145213463-145246870 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030336 Tnfrsf1b-001 145213463-145246870 protein_coding
  ENSMUST00000143055 Tnfrsf1b-002 145225416-145246870 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030336
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030336 10.811±0.79 8.179±0.81 3.593±0.62 0.631±0.25 21.883±6.54 14.915±1.32 3.175±0.12 3.330±0.34 6.439±2.82 16.553±3.09 0.847±0.26 17.896±5.62 7.288±3.17 0.367±0.12

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005031 IPI tumor necrosis factor-activated receptor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0006954 IMP inflammatory response
GO:0006955 IEA immune response
GO:0007166 IMP cell surface receptor signaling pathway
GO:0007568 IEA aging
GO:0008283 TAS cell proliferation
GO:0008630 IMP intrinsic apoptotic signaling pathway in response to DNA damage
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0030424 IEA axon
GO:0031625 IEA ubiquitin protein ligase binding
GO:0032496 IEA response to lipopolysaccharide
GO:0033209 IEA tumor necrosis factor-mediated signaling pathway
GO:0043025 IEA neuronal cell body
GO:0043196 IEA varicosity
GO:0045121 IDA membrane raft
GO:0048471 IEA perinuclear region of cytoplasm
GO:0050728 IMP negative regulation of inflammatory response
GO:0050779 IMP RNA destabilization
GO:0051044 IEA positive regulation of membrane protein ectodomain proteolysis
GO:0071222 IEA cellular response to lipopolysaccharide
GO:0071363 IEA cellular response to growth factor stimulus
GO:0097191 IMP extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070165 tnfrsf1b tumor necrosis factor receptor superfamily, member 1B protein_coding Danio_rerio
ENSG00000028137 TNFRSF1B tumor necrosis factor receptor superfamily, member 1B protein_coding Homo_sapiens

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