C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: MAD2 mitotic arrest deficient-like 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029003 Mad2l2 10090 + 4:148130384-148145699 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030860 Mad2l2-003 148140182-148145699 protein_coding
  ENSMUST00000084129 Mad2l2-001 148130915-148145699 protein_coding
  ENSMUST00000105707 Mad2l2-005 148140743-148145696 protein_coding
  ENSMUST00000105708 Mad2l2-008 148144790-148145451 retained_intron
  ENSMUST00000126261 Mad2l2-002 148130384-148140791 processed_transcript
  ENSMUST00000132698 Mad2l2-004 148140182-148145121 protein_coding
  ENSMUST00000140049 Mad2l2-006 148140724-148145120 protein_coding
  ENSMUST00000148742 Mad2l2-007 148140762-148143460 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030860ENSMUST00000084129ENSMUST00000105707ENSMUST00000105708
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030860 8.286±0.97 12.235±2.30 7.001±1.45 15.796±0.00 12.590±2.10 6.347±1.74 3.972±1.95 6.406±2.43 12.850±8.18 9.604±1.84 3.140±1.42 8.857±4.69 4.478±1.10 58.035±25.75
ENSMUST00000084129 6.177±0.51 N/A 3.745±0.02 20.509±0.00 16.043±11.39 N/A 3.347±1.56 2.968±0.67 2.510±0.49 2.357±0.04 3.253±1.50 5.946±3.50 5.710±4.97 51.855±25.34
ENSMUST00000105707 N/A N/A N/A 1.493±0.00 N/A 2.150±0.23 1.913±0.10 N/A 5.016±2.01 N/A 1.775±0.33 2.719±1.29 4.006±2.36 7.105±0.00
ENSMUST00000105708 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.611±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00087H CIL_00087H_0002 VISTA 4:147665245-148272946

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0001102 IEA RNA polymerase II activating transcription factor binding
GO:0001558 IEA regulation of cell growth
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005680 IEA anaphase-promoting complex
GO:0005737 IEA cytoplasm
GO:0005819 ISS spindle
GO:0006302 IEA double-strand break repair
GO:0006351 IEA transcription, DNA-templated
GO:0007015 IEA actin filament organization
GO:0007067 IEA mitotic nuclear division
GO:0008432 ISS JUN kinase binding
GO:0010719 IEA negative regulation of epithelial to mesenchymal transition
GO:0010944 IEA negative regulation of transcription by competitive promoter binding
GO:0016035 ISS zeta DNA polymerase complex
GO:0033138 ISS positive regulation of peptidyl-serine phosphorylation
GO:0042177 IEA negative regulation of protein catabolic process
GO:0042772 ISS DNA damage response, signal transduction resulting in transcription
GO:0043433 IEA negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0060564 ISS negative regulation of mitotic anaphase-promoting complex activity
GO:0090090 IEA negative regulation of canonical Wnt signaling pathway
GO:2000048 IEA negative regulation of cell-cell adhesion mediated by cadherin
GO:2000678 IEA negative regulation of transcription regulatory region DNA binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007096 MAD2L2 (1 of 2) MAD2 mitotic arrest deficient-like 2 (yeast) protein_coding Danio_rerio
ENSDARG00000042456 MAD2L2 (2 of 2) MAD2 mitotic arrest deficient-like 2 (yeast) protein_coding Danio_rerio
ENSG00000116670 MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) protein_coding Homo_sapiens

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