C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: diablo homolog (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029433 Diablo 10090 - 5:123509765-123524176 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000031385 Diablo-005 123517586-123524133 protein_coding
  ENSMUST00000111586 Diablo-006 123516264-123524133 protein_coding
  ENSMUST00000111587 Diablo-001 123511705-123524176 protein_coding
  ENSMUST00000125047 Diablo-007 123517936-123523491 retained_intron
  ENSMUST00000125652 Diablo-002 123509765-123524143 nonsense_mediated_decay
  ENSMUST00000139398 Diablo-004 123511705-123524142 retained_intron
  ENSMUST00000145152 Diablo-003 123515814-123524136 retained_intron
  ENSMUST00000149334 Diablo-008 123518037-123520754 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000111586ENSMUST00000111587ENSMUST00000139398ENSMUST00000145152
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000111586 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.396±0.00 15.583±0.00
ENSMUST00000111587 41.906±1.45 53.429±29.55 36.592±5.44 35.057±4.46 37.450±11.96 23.052±7.18 44.319±3.87 36.755±3.87 25.688±9.05 28.869±3.08 22.706±1.34 37.577±14.67 18.177±11.13 173.030±76.95
ENSMUST00000139398 N/A 75.236±12.12 N/A 6.547±3.67 25.359±3.74 16.649±5.49 N/A N/A 2.149±0.00 7.537±0.63 N/A 45.289±19.00 N/A N/A
ENSMUST00000145152 N/A N/A N/A N/A 4.120±0.00 N/A N/A N/A N/A N/A N/A 3.446±1.51 0.472±0.00 2.515±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005758 ISO mitochondrial intermembrane space
GO:0006919 IDA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0008631 IDA intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0008635 IDA activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
GO:0009898 IDA cytoplasmic side of plasma membrane
GO:0035631 IDA CD40 receptor complex
GO:0043065 IMP positive regulation of apoptotic process
GO:0051402 IDA neuron apoptotic process
GO:0097193 TAS intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014956 diablob diablo, IAP-binding mitochondrial protein b protein_coding Danio_rerio
ENSDARG00000035323 diabloa diablo, IAP-binding mitochondrial protein a protein_coding Danio_rerio
ENSG00000184047 DIABLO diablo, IAP-binding mitochondrial protein protein_coding Homo_sapiens

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