C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NADPH oxidase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031257 Nox1 10090 - X:134086421-134221956 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000033610 Nox1-001 134086421-134111854 protein_coding
  ENSMUST00000113275 Nox1-002 134087054-134111765 protein_coding
  ENSMUST00000159231 Nox1-004 134107733-134137711 protein_coding
  ENSMUST00000159259 Nox1-005 134087146-134111708 protein_coding
  ENSMUST00000162833 Nox1-003 134107733-134221956 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; ColonMuscleENSMUST00000033610
Transcript ID Colon Muscle
ENSMUST00000033610 5.257±1.36 0.550±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007BC CIL_0007BC_0002 CGP X:133936385-134086819
CIL_0000YO CIL_0000YO_0003 CGP X:134059187-134221956
CIL_0007B9 CIL_0007B9_0002 CGP X:134086421-134221956

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0003081 IMP regulation of systemic arterial blood pressure by renin-angiotensin
GO:0005515 IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005768 IMP endosome
GO:0005769 IEA early endosome
GO:0006801 IEA superoxide metabolic process
GO:0008284 IEA positive regulation of cell proliferation
GO:0010575 IEA positive regulation vascular endothelial growth factor production
GO:0015992 IEA proton transport
GO:0016021 IEA integral component of membrane
GO:0016175 IDA superoxide-generating NADPH oxidase activity
GO:0016477 IEA cell migration
GO:0030054 IEA cell junction
GO:0030171 IEA voltage-gated proton channel activity
GO:0030198 IMP extracellular matrix organization
GO:0042554 IDA superoxide anion generation
GO:0042743 IEA hydrogen peroxide metabolic process
GO:0043020 IEA NADPH oxidase complex
GO:0043410 IMP positive regulation of MAPK cascade
GO:0045726 IEA positive regulation of integrin biosynthetic process
GO:0046330 IMP positive regulation of JNK cascade
GO:0046872 IEA metal ion binding
GO:0048365 IEA Rac GTPase binding
GO:0051454 IEA intracellular pH elevation
GO:0055114 IEA oxidation-reduction process
GO:0071438 ISS invadopodium membrane
GO:0071455 IMP cellular response to hyperoxia
GO:0072592 IMP oxygen metabolic process
GO:1902177 IMP positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:1990451 IEA cellular stress response to acidic pH

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070062 nox1 NADPH oxidase 1 protein_coding Danio_rerio
ENSDARG00000087574 nox1 NADPH oxidase 1 protein_coding Danio_rerio
ENSG00000007952 NOX1 NADPH oxidase 1 protein_coding Homo_sapiens

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