C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: pannexin 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031934 Panx1 10090 - 9:15005161-15045478 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000056755 Panx1-002 15005785-15045478 nonsense_mediated_decay
  ENSMUST00000164273 Panx1-001 15005161-15045478 protein_coding
  ENSMUST00000166933 Panx1-003 15007918-15010508 retained_intron
  ENSMUST00000169288 Panx1-004 15010086-15043797 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000056755ENSMUST00000164273ENSMUST00000166933ENSMUST00000169288
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000056755 1.538±0.93 3.355±0.96 1.838±0.68 9.112±3.40 2.475±0.61 8.213±2.23 0.650±0.26 0.691±0.44 0.411±0.25 1.564±0.34 1.566±0.77 5.402±2.57 1.906±1.51 0.386±0.13
ENSMUST00000164273 2.052±1.11 1.946±0.62 0.897±0.00 18.936±2.90 4.896±1.14 6.699±1.44 0.401±0.14 0.563±0.15 0.366±0.41 2.017±0.71 1.095±0.37 6.983±2.73 0.560±0.48 0.352±0.14
ENSMUST00000166933 N/A N/A N/A 6.515±0.00 N/A N/A N/A N/A N/A N/A N/A 5.162±0.00 3.312±2.76 1.135±0.42
ENSMUST00000169288 N/A 7.321±0.18 N/A N/A 10.654±0.00 18.096±0.00 1.485±0.15 1.605±0.09 0.316±0.13 N/A N/A N/A N/A 2.734±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002020 IEA protease binding
GO:0002931 IGI response to ischemia
GO:0003779 IPI actin binding
GO:0005102 IEA receptor binding
GO:0005243 IEA gap junction channel activity
GO:0005262 ISS calcium channel activity
GO:0005515 IPI protein binding
GO:0005783 ISS endoplasmic reticulum
GO:0005886 IDA plasma membrane
GO:0005921 IEA gap junction
GO:0006812 IEA cation transport
GO:0006816 ISS calcium ion transport
GO:0007267 IEA cell-cell signaling
GO:0015267 IGI channel activity
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0022840 ISS leak channel activity
GO:0032059 IEA bleb
GO:0033198 IMP response to ATP
GO:0034214 ISS protein hexamerization
GO:0043234 IEA protein complex
GO:0044325 IEA ion channel binding
GO:0046982 IEA protein heterodimerization activity
GO:0050715 IMP positive regulation of cytokine secretion
GO:0050717 IMP positive regulation of interleukin-1 alpha secretion
GO:0050718 IMP positive regulation of interleukin-1 beta secretion
GO:0051015 IDA actin filament binding
GO:0055077 ISS gap junction hemi-channel activity
GO:0055085 IGI transmembrane transport
GO:0070588 IEA calcium ion transmembrane transport
GO:0097110 IEA scaffold protein binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014910 panx1b pannexin 1b protein_coding Danio_rerio
ENSDARG00000025285 panx1a pannexin 1a protein_coding Danio_rerio
ENSG00000110218 PANX1 pannexin 1 protein_coding Homo_sapiens

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