C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nucleotide-binding oligomerization domain containing 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000038058 Nod1 10090 - 6:54923942-54972612 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000060655 Nod1-201 54923942-54972612 protein_coding
  ENSMUST00000168172 Nod1-202 54923942-54971661 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000060655ENSMUST00000168172
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000060655 16.847±3.39 11.047±1.35 7.690±0.33 0.671±0.24 23.270±3.40 9.164±2.86 8.027±0.51 5.832±0.74 2.464±0.84 31.810±4.22 3.375±0.35 11.200±6.46 1.381±0.85 0.335±0.15
ENSMUST00000168172 4.765±0.00 N/A N/A 0.350±0.00 2.779±0.00 N/A N/A N/A 0.333±0.00 N/A N/A 3.448±1.17 N/A 0.111±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006I3 CIL_0006I3_0003 CGP 6:54816916-54972612
CIL_000408 CIL_000408_0002 CGP 6:54923942-54992950

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002606 IMP positive regulation of dendritic cell antigen processing and presentation
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0006919 IEA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006952 RCA defense response
GO:0016045 ISS detection of bacterium
GO:0016323 ISS basolateral plasma membrane
GO:0032755 IGI positive regulation of interleukin-6 production
GO:0032760 IGI positive regulation of tumor necrosis factor production
GO:0032874 IDA positive regulation of stress-activated MAPK cascade
GO:0035556 ISS intracellular signal transduction
GO:0042228 ISS interleukin-8 biosynthetic process
GO:0042742 ISS defense response to bacterium
GO:0042802 IEA identical protein binding
GO:0042803 IEA protein homodimerization activity
GO:0043123 IDA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043280 IEA positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045087 IEA innate immune response
GO:0046330 IDA positive regulation of JNK cascade
GO:0050700 IEA CARD domain binding
GO:0050830 IGI defense response to Gram-positive bacterium
GO:0051092 ISS positive regulation of NF-kappaB transcription factor activity
GO:0070374 IDA positive regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036308 nod1 nucleotide-binding oligomerization domain containing 1 protein_coding Danio_rerio
ENSG00000106100 NOD1 nucleotide-binding oligomerization domain containing 1 protein_coding Homo_sapiens

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