C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000038290 Smg6 10090 + 11:74925823-75164448 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000045281 Smg6-001 74925823-75164448 protein_coding
  ENSMUST00000130145 Smg6-003 74930520-75164448 nonsense_mediated_decay
  ENSMUST00000135522 Smg6-002 74989361-74992206 retained_intron
  ENSMUST00000140197 Smg6-004 74993853-75139369 protein_coding
  ENSMUST00000142038 Smg6-005 75132435-75139369 processed_transcript
  ENSMUST00000153226 Smg6-006 75159633-75163182 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000045281ENSMUST00000130145
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000045281 9.907±3.20 8.710±0.85 7.760±2.16 10.500±1.40 8.228±1.15 7.499±0.71 4.467±0.43 8.289±1.18 4.865±1.53 9.406±1.15 3.830±0.66 13.596±3.73 9.057±3.45 23.355±2.75
ENSMUST00000130145 7.752±1.33 N/A 8.555±1.49 8.829±0.00 10.249±0.72 7.355±0.70 4.440±0.73 9.713±1.19 3.310±1.24 10.186±1.21 N/A 15.015±0.10 12.737±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007RP CIL_0007RP_0002 VISTA 11:74746156-75348336
CIL_00093G CIL_00093G_0002 VISTA 11:74749027-75350435

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000184 ISS nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000723 ISS telomere maintenance
GO:0000781 IEA chromosome, telomeric region
GO:0004521 ISS endoribonuclease activity
GO:0005515 IEA protein binding
GO:0005634 ISS nucleus
GO:0005730 IEA nucleolus
GO:0005737 ISS cytoplasm
GO:0005829 ISS cytosol
GO:0035145 ISS exon-exon junction complex
GO:0042162 ISS telomeric DNA binding
GO:0046872 IEA metal ion binding
GO:0090502 IEA RNA phosphodiester bond hydrolysis, endonucleolytic

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075957 smg6 Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans) protein_coding Danio_rerio
ENSG00000070366 SMG6 SMG6 nonsense mediated mRNA decay factor protein_coding Homo_sapiens

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