Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Accession	Transcript Name	Contained in Gene	Tax ID	Strand	Position	Biotype
Transcript Info
Description:	hypermethylated in cancer 1
ENSMUST00000055619	Hic1-001	ENSMUSG00000043099	10090	-	11:75164565-75169519	protein_coding

Expression Patterns

Transcript ID	Adipose	Adrenal	Bladder	Brain	Breast	Colon	Heart	Kidney	Liver	Lung	Muscle	Ovary	Placenta	Testis
ENSMUST00000055619	9.216±4.44	1.974±0.54	3.072±0.22	1.071±0.71	4.123±0.92	4.925±1.59	1.313±0.36	0.876±0.26	0.408±0.14	3.495±1.36	1.167±0.88	12.779±4.61	15.040±8.83	0.405±0.11

Conserved Regions
Region ID	Sub-Region	Region Type	Position
CIL_0007RP	CIL_0007RP_0002	VISTA	11:74746156-75348336
CIL_00093G	CIL_00093G_0002	VISTA	11:74749027-75350435
CIL_0007KQ	CIL_0007KQ_0002	UCNEbase	11:75016990-75215448

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0000122	IEA	negative regulation of transcription from RNA polymerase II promoter
GO:0003700	IEA	sequence-specific DNA binding transcription factor activity
GO:0005634	IEA	nucleus
GO:0005737	IEA	cytoplasm
GO:0008630	IEA	intrinsic apoptotic signaling pathway in response to DNA damage
GO:0030178	IEA	negative regulation of Wnt signaling pathway
GO:0042826	IEA	histone deacetylase binding
GO:0043565	IEA	sequence-specific DNA binding
GO:0046872	IEA	metal ion binding

Homologs
ENSEMBL Accession	Gene Name	Biotype	Species	E-Value	Bit Score
ENST00000322941	HIC1-005	protein_coding	Homo_sapiens	0	2627
ENST00000399849	HIC1-201	protein_coding	Homo_sapiens	0	2833
ENST00000571875	HIC1-002	protein_coding	Homo_sapiens	0	688
ENST00000571990	HIC1-003	protein_coding	Homo_sapiens	0	808
ENST00000574370	HIC1-001	protein_coding	Homo_sapiens	0	411
ENST00000576444	HIC1-004	protein_coding	Homo_sapiens	0	475
ENST00000619757	HIC1-006	protein_coding	Homo_sapiens	0	2833

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