C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein phosphatase 3, catalytic subunit, beta isoform
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000159027 Ppp3cb-001 ENSMUSG00000021816 10090 - 14:20499364-20546573 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainLiverENSMUST00000159027
Transcript ID Adrenal Brain Liver
ENSMUST00000159027 0.602±0.00 4.056±0.00 0.891±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000090 CIL_000090_0002 CGP 14:20482864-20546573
CIL_00008Z CIL_00008Z_0002 CGP 14:20499364-20618354

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001915 IMP negative regulation of T cell mediated cytotoxicity
GO:0004722 IDA protein serine/threonine phosphatase activity
GO:0004723 TAS calcium-dependent protein serine/threonine phosphatase activity
GO:0005509 ISS calcium ion binding
GO:0005515 IPI protein binding
GO:0005516 ISS calmodulin binding
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0005955 ISS calcineurin complex
GO:0006468 IMP protein phosphorylation
GO:0006470 IMP protein dephosphorylation
GO:0007507 IMP heart development
GO:0008144 ISS drug binding
GO:0010468 IMP regulation of gene expression
GO:0017156 IDA calcium ion-dependent exocytosis
GO:0019899 ISS enzyme binding
GO:0030018 IDA Z disc
GO:0030217 IMP T cell differentiation
GO:0030315 IDA T-tubule
GO:0030346 ISS protein phosphatase 2B binding
GO:0031987 IMP locomotion involved in locomotory behavior
GO:0033192 IMP calmodulin-dependent protein phosphatase activity
GO:0034097 IMP response to cytokine
GO:0035176 IEA social behavior
GO:0035690 ISS cellular response to drug
GO:0035774 IMP positive regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0043029 IMP T cell homeostasis
GO:0046983 IEA protein dimerization activity
GO:0050796 ISS regulation of insulin secretion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000342558 PPP3CB-002 protein_coding Homo_sapiens 0 2362
ENST00000360663 PPP3CB-001 protein_coding Homo_sapiens 0 4602
ENST00000394828 PPP3CB-201 protein_coding Homo_sapiens 0 2423
ENST00000394829 PPP3CB-202 protein_coding Homo_sapiens 0 4567
ENST00000430762 PPP3CB-003 protein_coding Homo_sapiens 0 804
ENST00000495897 PPP3CB-004 processed_transcript Homo_sapiens 0 893

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