C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cytochrome P450, family 51, subfamily A, polypeptide 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000003100 CYP51A1-001 ENSG00000001630 9606 - 7:92112151-92134530 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000003100
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000003100 8.532±0.00 5.273±0.00 1.001±0.00 19.974±4.77 5.314±0.53 4.276±1.98 2.919±0.07 22.532±1.26 10.989±4.92 8.866±5.24 3.213±0.00 17.652±4.28 6.107±1.74 26.035±4.25

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006E3 CIL_0006E3_0001 CGP 7:91940867-92142952

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005506 IEA iron ion binding
GO:0005783 IDA endoplasmic reticulum
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006694 IDA steroid biosynthetic process
GO:0006695 TAS cholesterol biosynthetic process
GO:0006805 TAS xenobiotic metabolic process
GO:0008398 IDA sterol 14-demethylase activity
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0016125 TAS sterol metabolic process
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 IDA:IEA heme binding
GO:0033488 IEA cholesterol biosynthetic process via 24,25-dihydrolanosterol
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0044281 TAS small molecule metabolic process
GO:0055114 IEA oxidation-reduction process
GO:0070988 IEA demethylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000001507 Cyp51-001 protein_coding Mus_musculus 0 1832
ENSMUST00000151539 Cyp51-003 retained_intron Mus_musculus 0 743
ENSMUST00000129448 Cyp51-002 processed_transcript Mus_musculus 0 224

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