C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein phosphatase 2, regulatory subunit A, alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000322088 PPP2R1A-001 ENSG00000105568 9606 + 19:52190039-52229533 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBreastHeartLiverLungOvaryTestisENST00000322088
Transcript ID Bladder Breast Heart Liver Lung Ovary Testis
ENST00000322088 0.722±0.00 2.148±0.00 0.954±0.00 1.058±0.00 1.664±0.00 2.046±0.00 0.923±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000086 TAS G2/M transition of mitotic cell cycle
GO:0000159 TAS protein phosphatase type 2A complex
GO:0000184 TAS nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000188 NAS inactivation of MAPK activity
GO:0000278 TAS mitotic cell cycle
GO:0000775 IDA chromosome, centromeric region
GO:0003823 IPI antigen binding
GO:0004722 IEA protein serine/threonine phosphatase activity
GO:0005488 IEA binding
GO:0005515 IPI:IEA protein binding
GO:0005634 NAS nucleus
GO:0005739 NAS mitochondrion
GO:0005829 TAS cytosol
GO:0006275 NAS regulation of DNA replication
GO:0006355 NAS regulation of transcription, DNA-templated
GO:0006461 TAS protein complex assembly
GO:0006470 TAS protein dephosphorylation
GO:0006672 NAS ceramide metabolic process
GO:0006915 TAS apoptotic process
GO:0007059 IDA chromosome segregation
GO:0007084 TAS mitotic nuclear envelope reassembly
GO:0008380 NAS RNA splicing
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0008601 TAS protein phosphatase type 2A regulator activity
GO:0010033 NAS response to organic substance
GO:0010467 TAS gene expression
GO:0015630 NAS microtubule cytoskeleton
GO:0016020 NAS membrane
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0019932 NAS second-messenger-mediated signaling
GO:0030111 NAS regulation of Wnt signaling pathway
GO:0030155 NAS regulation of cell adhesion
GO:0030308 NAS negative regulation of cell growth
GO:0040008 NAS regulation of growth
GO:0042518 NAS negative regulation of tyrosine phosphorylation of Stat3 protein
GO:0045595 NAS regulation of cell differentiation
GO:0046982 IPI protein heterodimerization activity
GO:0070062 IDA extracellular vesicular exosome
GO:0070262 IEA peptidyl-serine dephosphorylation
GO:2001241 IEA positive regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000007708 Ppp2r1a-001 protein_coding Mus_musculus 0 2608
ENSDART00000016860 ppp2r1b-001 protein_coding Danio_rerio 0 1075
ENSMUST00000173658 Ppp2r1a-007 nonsense_mediated_decay Mus_musculus 0 704
ENSMUST00000173359 Ppp2r1a-006 retained_intron Mus_musculus 0 625
ENSMUST00000147983 Ppp2r1a-002 protein_coding Mus_musculus 0 305
ENSMUST00000136975 Ppp2r1a-003 retained_intron Mus_musculus 0 268
ENSMUST00000173269 Neu1-002 retained_intron Mus_musculus 0.000008 58

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