C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000375006 PFKFB1-001 ENSG00000158571 9606 - X:54932961-54994078 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderHeartKidneyMuscleOvaryTestisENST00000375006
Transcript ID Adipose Bladder Heart Kidney Muscle Ovary Testis
ENST00000375006 1.110±0.00 0.104±0.00 0.056±0.00 3.331±0.00 1.483±0.00 0.063±0.00 0.314±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003873 TAS:IEA 6-phosphofructo-2-kinase activity
GO:0004331 IDA:IEA fructose-2,6-bisphosphate 2-phosphatase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005829 TAS cytosol
GO:0005975 TAS carbohydrate metabolic process
GO:0006000 IEA fructose metabolic process
GO:0006003 IDA:IEA fructose 2,6-bisphosphate metabolic process
GO:0006006 TAS glucose metabolic process
GO:0006094 TAS gluconeogenesis
GO:0006096 TAS glycolytic process
GO:0006112 TAS energy reserve metabolic process
GO:0016301 IEA kinase activity
GO:0016311 IEA dephosphorylation
GO:0019900 IEA kinase binding
GO:0031100 IEA organ regeneration
GO:0032868 IEA response to insulin
GO:0033133 IEA positive regulation of glucokinase activity
GO:0033762 IEA response to glucagon
GO:0035556 TAS intracellular signal transduction
GO:0042594 IEA response to starvation
GO:0042802 IEA identical protein binding
GO:0043540 IDA 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex
GO:0044281 TAS small molecule metabolic process
GO:0046835 IEA carbohydrate phosphorylation
GO:0051384 IEA response to glucocorticoid
GO:0051591 IEA response to cAMP
GO:0070095 IEA fructose-6-phosphate binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000112713 Pfkfb1-002 protein_coding Mus_musculus 0 2045
ENSMUST00000080884 Pfkfb1-001 protein_coding Mus_musculus 0 1847
ENSMUST00000150783 Pfkfb1-003 retained_intron Mus_musculus 0 1539
ENSMUST00000153221 Pfkfb1-004 protein_coding Mus_musculus 0 774
ENSMUST00000154528 Pfkfb1-007 processed_transcript Mus_musculus 0 394
ENSMUST00000124381 Pfkfb1-005 processed_transcript Mus_musculus 0 322
ENSMUST00000142848 Pfkfb1-006 processed_transcript Mus_musculus 0 259

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