C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: lipoic acid synthetase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000381846 LIAS-002 ENSG00000121897 9606 + 4:39459072-39477621 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000381846
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000381846 0.734±0.00 0.841±0.00 0.394±0.00 0.306±0.00 2.928±0.00 0.463±0.31 1.003±0.00 0.605±0.03 0.708±0.37 1.123±0.56 1.176±0.65 1.586±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002TV CIL_0002TV_0002 CGP 4:39454124-39477653
CIL_000278 CIL_000278_0002 CGP 4:39459000-39528311

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0005739 ISS mitochondrion
GO:0006954 ISS inflammatory response
GO:0006979 ISS response to oxidative stress
GO:0009107 ISS lipoate biosynthetic process
GO:0009249 IEA protein lipoylation
GO:0016992 ISS lipoate synthase activity
GO:0032496 ISS response to lipopolysaccharide
GO:0046872 IEA metal ion binding
GO:0051536 IEA iron-sulfur cluster binding
GO:0051539 IEA 4 iron, 4 sulfur cluster binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000031101 Lias-001 protein_coding Mus_musculus 0 728
ENSMUST00000126036 Lias-004 retained_intron Mus_musculus 0 470
ENSMUST00000122026 Lias-003 protein_coding Mus_musculus 0 446
ENSMUST00000139847 Lias-002 retained_intron Mus_musculus 0 422

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