C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mitogen-activated protein kinase kinase kinase 12
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000547488 MAP3K12-002 ENSG00000139625 9606 - 12:53481121-53499456 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainENST00000547488
Transcript ID Brain
ENST00000547488 7.237±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009B4 CIL_0009B4_0001 VISTA 12:53396852-53997557
CIL_00033G CIL_00033G_0002 CGP 12:53452102-53500063

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000186 IEA activation of MAPKK activity
GO:0004672 TAS:IEA protein kinase activity
GO:0004674 ISS protein serine/threonine kinase activity
GO:0004709 IEA MAP kinase kinase kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 TAS cytoplasm
GO:0005829 ISS cytosol
GO:0005886 ISS plasma membrane
GO:0006468 ISS:IEA protein phosphorylation
GO:0007254 ISS JNK cascade
GO:0016020 ISS membrane
GO:0016572 ISS histone phosphorylation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018105 ISS peptidyl-serine phosphorylation
GO:0018107 ISS peptidyl-threonine phosphorylation
GO:0019901 IPI protein kinase binding
GO:0035556 TAS intracellular signal transduction
GO:0042803 ISS protein homodimerization activity
GO:0046777 ISS:IEA protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000023812 Map3k12-002 protein_coding Mus_musculus 0 3653
ENSMUST00000169377 Map3k12-001 protein_coding Mus_musculus 0 3605
ENSMUST00000171565 Map3k12-003 protein_coding Mus_musculus 0 3605
ENSDART00000062432 MAP3K12-201 protein_coding Danio_rerio 0 809
ENSMUST00000096145 Gm10337-201 protein_coding Mus_musculus 0 259
ENSMUST00000169367 Map3k12-006 protein_coding Mus_musculus 0.00000008 64
ENSMUST00000169162 Map3k12-008 protein_coding Mus_musculus 0.0000003 62
ENSMUST00000164343 Map3k12-004 processed_transcript Mus_musculus 0.00005 55

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