C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glycine receptor, alpha 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000012019 glra1 7955 + 14:26827161-26914777 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000005499 glra1-201 26827181-26914777 protein_coding
  ENSDART00000047680 glra1-202 26827181-26914777 protein_coding
  ENSDART00000066197 glra1-203 26827181-26914777 protein_coding
  ENSDART00000136733 glra1-001 26827161-26914777 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000005499ENSDART00000047680ENSDART00000136733
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000005499 2.911±0.00 0.035±0.00 N/A 0.026±0.00 0.186±0.00
ENSDART00000047680 1.308±1.28 N/A N/A N/A N/A
ENSDART00000136733 1.604±1.56 N/A 0.073±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005230 IEA extracellular ligand-gated ion channel activity
GO:0005254 IEA chloride channel activity
GO:0005886 IEA plasma membrane
GO:0005887 IEA integral to plasma membrane
GO:0006810 IEA transport
GO:0006811 IEA ion transport
GO:0006821 IEA chloride transport
GO:0007417 IMP central nervous system development
GO:0016020 IEA membrane
GO:0016021 IEA integral to membrane
GO:0016594 IEA glycine binding
GO:0016934 IEA extracellular-glycine-gated chloride channel activity
GO:0022824 IEA transmitter-gated ion channel activity
GO:0030054 IEA cell junction
GO:0034707 IEA chloride channel complex
GO:0043200 IDA response to amino acid
GO:0045202 IEA synapse
GO:0045211 IEA postsynaptic membrane
GO:0045664 IMP regulation of neuron differentiation
GO:1902476 IDA chloride transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000145888 GLRA1 glycine receptor, alpha 1 protein_coding Homo_sapiens
ENSMUSG00000000263 Glra1 glycine receptor, alpha 1 subunit protein_coding Mus_musculus

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