C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: thyroid hormone receptor beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000021163 thrb 7955 - 19:19505437-19646473 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000017869 thrb-001 19506361-19646473 nonsense_mediated_decay
  ENSDART00000142170 thrb-002 19507033-19515035 processed_transcript
  ENSDART00000151766 thrb-003 19505437-19646460 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000017869ENSDART00000151766
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000017869 4.149±0.00 1.857±0.00 N/A 0.370±0.00 N/A
ENSDART00000151766 6.908±0.00 3.958±2.89 7.364±0.00 0.446±0.00 0.992±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00025B CIL_00025B_0001 CGP 19:19388563-19646473

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001076 IDA RNA polymerase II transcription factor binding transcription factor activity
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0004887 IEA thyroid hormone receptor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-dependent
GO:0006357 ISS regulation of transcription from RNA polymerase II promoter
GO:0006366 ISS transcription from RNA polymerase II promoter
GO:0008270 IEA zinc ion binding
GO:0030522 ISS intracellular receptor signaling pathway
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IEA sequence-specific DNA binding
GO:0046872 IEA metal ion binding
GO:0070324 ISS thyroid hormone binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000151090 THRB thyroid hormone receptor, beta protein_coding Homo_sapiens
ENSMUSG00000021779 Thrb thyroid hormone receptor beta protein_coding Mus_musculus

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