C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: GDP-mannose 4,6-dehydratase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000026629 gmds 7955 - 20:26738616-26852157 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000046764 gmds-001 26738616-26852157 protein_coding
  ENSDART00000103234 gmds-201 26739061-26852108 protein_coding
  ENSDART00000143267 gmds-002 26836916-26852157 protein_coding
  ENSDART00000146326 gmds-003 26805419-26852129 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000046764ENSDART00000103234ENSDART00000143267ENSDART00000146326
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000046764 4.829±4.67 5.158±4.12 9.294±6.58 0.763±0.00 4.059±0.00
ENSDART00000103234 N/A 1.278±0.00 N/A N/A N/A
ENSDART00000143267 0.106±0.00 0.172±0.10 N/A N/A N/A
ENSDART00000146326 0.239±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005SP CIL_0005SP_0001 CGP 20:26731984-26852157
CIL_0005MS CIL_0005MS_0001 CGP 20:26738616-26895718

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0005622 IEA intracellular
GO:0007219 IMP Notch signaling pathway
GO:0008417 IMP fucosyltransferase activity
GO:0008446 IEA GDP-mannose 4,6-dehydratase activity
GO:0008831 IEA dTDP-4-dehydrorhamnose reductase activity
GO:0010842 IMP retina layer formation
GO:0019673 IEA GDP-mannose metabolic process
GO:0021564 IMP vagus nerve development
GO:0021744 IMP dorsal motor nucleus of vagus nerve development
GO:0036065 IMP fucosylation
GO:0042351 ISS 'de novo' GDP-L-fucose biosynthetic process
GO:0044237 IEA cellular metabolic process
GO:0045226 IEA extracellular polysaccharide biosynthetic process
GO:0050662 IEA coenzyme binding
GO:0070401 ISS NADP+ binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000112699 GMDS GDP-mannose 4,6-dehydratase protein_coding Homo_sapiens
ENSMUSG00000038372 Gmds GDP-mannose 4, 6-dehydratase protein_coding Mus_musculus

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