C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: pleckstrin homology-like domain, family A, member 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000037804 phlda3 7955 - 23:5806309-5809109 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000055087 phlda3-001 5806309-5809109 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyMuscleENSDART00000055087
Transcript ID Brain Heart Kidney Muscle
ENSDART00000055087 4.793±1.70 2.610±2.16 0.895±0.25 6.825±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005546 ISS phosphatidylinositol-4,5-bisphosphate binding
GO:0005547 ISS phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005622 ISS intracellular
GO:0005737 IEA cytoplasm
GO:0005886 ISS plasma membrane
GO:0006915 IEA apoptotic process
GO:0010314 ISS phosphatidylinositol-5-phosphate binding
GO:0016020 IEA membrane
GO:0032266 ISS phosphatidylinositol-3-phosphate binding
GO:0042771 ISS intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043065 ISS positive regulation of apoptotic process
GO:0043325 ISS phosphatidylinositol-3,4-bisphosphate binding
GO:0051898 ISS negative regulation of protein kinase B signaling
GO:0080025 ISS phosphatidylinositol-3,5-bisphosphate binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000174307 PHLDA3 pleckstrin homology-like domain, family A, member 3 protein_coding Homo_sapiens
ENSMUSG00000041801 Phlda3 pleckstrin homology-like domain, family A, member 3 protein_coding Mus_musculus

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