C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ubiquitin-conjugating enzyme E2Nb
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000045877 ube2nb 7955 - 4:1670194-1678947 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000067433 ube2nb-001 1670194-1678947 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000067433
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000067433 22.308±14.23 19.234±3.97 12.277±12.24 2.040±0.00 8.545±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000XV CIL_0000XV_0001 CGP 4:1648879-1678947
CIL_0005X9 CIL_0005X9_0001 CGP 4:1670194-1685437

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000724 ISS double-strand break repair via homologous recombination
GO:0000729 ISS DNA double-strand break processing
GO:0005634 ISS nucleus
GO:0006301 ISS postreplication repair
GO:0016567 ISS protein ubiquitination
GO:0016574 ISS histone ubiquitination
GO:0016874 IEA ligase activity
GO:0016881 IEA acid-amino acid ligase activity
GO:0031058 ISS positive regulation of histone modification
GO:0031372 ISS UBC13-MMS2 complex
GO:0033182 ISS regulation of histone ubiquitination
GO:0042769 IDA DNA damage response, detection of DNA damage
GO:0043123 ISS positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043130 ISS ubiquitin binding
GO:0045739 ISS positive regulation of DNA repair
GO:0050852 ISS T cell receptor signaling pathway
GO:0051092 ISS positive regulation of NF-kappaB transcription factor activity
GO:0051443 ISS positive regulation of ubiquitin-protein ligase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000177889 UBE2N ubiquitin-conjugating enzyme E2N protein_coding Homo_sapiens
ENSMUSG00000074781 Ube2n ubiquitin-conjugating enzyme E2N protein_coding Mus_musculus

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