C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: notch homolog 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000052139 notch3 7955 - 3:54167733-54197430 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000073930 notch3-001 54167733-54197430 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000073930
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000073930 0.479±0.30 1.736±2.41 0.196±0.02 0.413±0.00 2.280±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001840 IGI neural plate development
GO:0001889 IGI liver development
GO:0005509 IEA calcium ion binding
GO:0005515 IEA protein binding
GO:0007219 IEA Notch signaling pathway
GO:0007275 IEA multicellular organismal development
GO:0016020 IEA membrane
GO:0016021 IEA integral to membrane
GO:0021654 IGI rhombomere boundary formation
GO:0021865 IMP symmetric radial glial cell division in forebrain
GO:0030154 IEA cell differentiation
GO:0035019 IEP somatic stem cell maintenance
GO:0048259 IGI regulation of receptor-mediated endocytosis
GO:0048793 IMP pronephros development
GO:0048936 IGI peripheral nervous system neuron axonogenesis
GO:0050768 IEP negative regulation of neurogenesis
GO:0050793 IEA regulation of developmental process
GO:0097150 IMP neuronal stem cell maintenance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000074181 NOTCH3 notch 3 protein_coding Homo_sapiens
ENSMUSG00000038146 Notch3 notch 3 protein_coding Mus_musculus

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