C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NK2 transcription factor related 2a
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000053298 nkx2.2a 7955 + 17:42929655-42937363 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000081396 nkx2.2a-002 42929655-42937363 protein_coding
  ENSDART00000140549 nkx2.2a-001 42934991-42937363 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainKidneyMuscleENSDART00000081396ENSDART00000140549
Transcript ID Brain Kidney Muscle
ENSDART00000081396 2.479±0.76 0.135±0.01 0.486±0.00
ENSDART00000140549 4.650±2.60 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005634 IEA nucleus
GO:0006355 IEA regulation of transcription, DNA-dependent
GO:0007275 IEA multicellular organismal development
GO:0008045 IMP motor neuron axon guidance
GO:0008347 IMP glial cell migration
GO:0014044 IMP Schwann cell development
GO:0021508 IMP floor plate formation
GO:0021514 IGI ventral spinal cord interneuron differentiation
GO:0021529 IMP spinal cord oligodendrocyte cell differentiation
GO:0021530 IMP spinal cord oligodendrocyte cell fate specification
GO:0031018 IMP endocrine pancreas development
GO:0033504 IMP floor plate development
GO:0043565 IEA sequence-specific DNA binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000125820 NKX2-2 NK2 homeobox 2 protein_coding Homo_sapiens
ENSMUSG00000027434 Nkx2-2 NK2 homeobox 2 protein_coding Mus_musculus

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