C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sonic hedgehog a
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000068567 shha 7955 + 7:43613639-43620963 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000099204 shha-201 43613639-43620963 protein_coding
  ENSDART00000149395 shha-001 43613639-43620963 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyMuscleENSDART00000099204ENSDART00000149395
Transcript ID Brain Heart Kidney Muscle
ENSDART00000099204 4.243±0.00 0.061±0.02 N/A 0.079±0.00
ENSDART00000149395 1.546±0.88 N/A 0.158±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001708 IMP cell fate specification
GO:0001756 IGI somitogenesis
GO:0001839 IMP neural plate morphogenesis
GO:0001947 IDA heart looping
GO:0005576 IEA extracellular region
GO:0005615 IEA extracellular space
GO:0005886 IEA plasma membrane
GO:0006508 IEA proteolysis
GO:0007154 IEA cell communication
GO:0007224 IGI smoothened signaling pathway
GO:0007267 IEA cell-cell signaling
GO:0007275 IEA multicellular organismal development
GO:0007368 IDA determination of left/right symmetry
GO:0007399 IMP nervous system development
GO:0007411 IMP axon guidance
GO:0007417 IMP central nervous system development
GO:0007420 IMP brain development
GO:0007517 IMP muscle organ development
GO:0008015 IMP blood circulation
GO:0008233 IEA peptidase activity
GO:0008285 IMP negative regulation of cell proliferation
GO:0009952 IGI anterior/posterior pattern specification
GO:0009953 IMP dorsal/ventral pattern formation
GO:0010001 IMP glial cell differentiation
GO:0010002 IMP cardioblast differentiation
GO:0010468 IDA regulation of gene expression
GO:0016020 IEA membrane
GO:0016539 IEA intein-mediated protein splicing
GO:0016787 IEA hydrolase activity
GO:0021508 IMP floor plate formation
GO:0021536 IGI diencephalon development
GO:0021984 IDA adenohypophysis development
GO:0030182 IMP neuron differentiation
GO:0030900 IMP forebrain development
GO:0030902 IMP hindbrain development
GO:0030947 IMP regulation of vascular endothelial growth factor receptor signaling pathway
GO:0031016 IDA pancreas development
GO:0031018 IDA endocrine pancreas development
GO:0031076 IMP embryonic camera-type eye development
GO:0032835 IMP glomerulus development
GO:0033339 IMP pectoral fin development
GO:0033504 IMP floor plate development
GO:0035143 IMP caudal fin morphogenesis
GO:0042063 IGI gliogenesis
GO:0042462 IMP eye photoreceptor cell development
GO:0042476 IMP odontogenesis
GO:0042694 IMP muscle cell fate specification
GO:0043010 IDA camera-type eye development
GO:0045494 IMP photoreceptor cell maintenance
GO:0046872 IEA metal ion binding
GO:0048557 IMP embryonic digestive tract morphogenesis
GO:0048618 IMP post-embryonic foregut morphogenesis
GO:0048663 IGI neuron fate commitment
GO:0048702 IMP embryonic neurocranium morphogenesis
GO:0048703 IGI embryonic viscerocranium morphogenesis
GO:0048741 IGI skeletal muscle fiber development
GO:0048795 IMP swim bladder morphogenesis
GO:0048839 IGI inner ear development
GO:0055002 IMP striated muscle cell development
GO:0060956 IGI endocardial cell differentiation
GO:0061035 IGI regulation of cartilage development
GO:2000223 IDA regulation of BMP signaling pathway involved in heart jogging

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000164690 SHH sonic hedgehog protein_coding Homo_sapiens
ENSMUSG00000002633 Shh sonic hedgehog protein_coding Mus_musculus

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