C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: forkhead box C1a
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000091481 foxc1a 7955 - 2:868215-870389 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000122732 foxc1a-001 868215-870389 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000122732
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000122732 4.386±1.49 12.559±7.59 7.617±4.37 0.048±0.00 2.194±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IBA negative regulation of transcription from RNA polymerase II promoter
GO:0001568 IGI blood vessel development
GO:0001756 IMP somitogenesis
GO:0001944 IMP vasculature development
GO:0003677 IEA DNA binding
GO:0003690 IBA double-stranded DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003705 IBA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005634 IEA nucleus
GO:0005667 IBA transcription factor complex
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-dependent
GO:0006366 IBA transcription from RNA polymerase II promoter
GO:0007219 IBA Notch signaling pathway
GO:0008134 IBA transcription factor binding
GO:0008301 IBA DNA binding, bending
GO:0030325 IGI adrenal gland development
GO:0031490 IBA chromatin DNA binding
GO:0039021 IGI pronephric glomerulus development
GO:0043010 IGI camera-type eye development
GO:0043066 IBA negative regulation of apoptotic process
GO:0043114 IGI regulation of vascular permeability
GO:0043565 IEA sequence-specific DNA binding
GO:0045944 IBA positive regulation of transcription from RNA polymerase II promoter
GO:0046620 IBA regulation of organ growth
GO:0048010 IBA vascular endothelial growth factor receptor signaling pathway
GO:0051090 IBA regulation of sequence-specific DNA binding transcription factor activity
GO:0061386 IMP closure of optic fissure
GO:0072149 IGI glomerular visceral epithelial cell fate commitment

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000054598 FOXC1 forkhead box C1 protein_coding Homo_sapiens
ENSMUSG00000050295 Foxc1 forkhead box C1 protein_coding Mus_musculus

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