C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: FK506 binding protein 4, 59kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000004478 FKBP4 9606 + 12:2794953-2805423 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000001008 FKBP4-001 2794953-2805423 protein_coding
  ENST00000538622 FKBP4-004 2796681-2797871 protein_coding
  ENST00000539181 FKBP4-006 2801178-2801803 protein_coding
  ENST00000540260 FKBP4-003 2795657-2797202 processed_transcript
  ENST00000543037 FKBP4-005 2798767-2800465 retained_intron
  ENST00000543769 FKBP4-002 2795069-2797282 nonsense_mediated_decay
  ENST00000544366 FKBP4-007 2803197-2805410 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENST00000001008ENST00000543037
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000001008 17.106±0.00 10.657±0.00 2.865±0.00 11.860±5.59 9.404±4.21 29.529±24.82 3.137±0.00 4.052±0.00 3.139±0.00 3.375±0.00 11.685±5.36 11.917±5.68 52.605±33.99
ENST00000543037 31.617±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000413 IEA protein peptidyl-prolyl isomerization
GO:0003755 IEA:IDA peptidyl-prolyl cis-trans isomerase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005525 IEA GTP binding
GO:0005528 IBA FK506 binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005789 IBA endoplasmic reticulum membrane
GO:0005829 ISS cytosol
GO:0005874 IEA microtubule
GO:0006457 IEA:TAS protein folding
GO:0006463 IEA steroid hormone receptor complex assembly
GO:0006825 IEA copper ion transport
GO:0007566 IEA embryo implantation
GO:0010977 ISS negative regulation of neuron projection development
GO:0030521 IEA androgen receptor signaling pathway
GO:0030674 TAS protein binding, bridging
GO:0030850 IEA prostate gland development
GO:0031072 IPI heat shock protein binding
GO:0031111 ISS negative regulation of microtubule polymerization or depolymerization
GO:0031115 IEA negative regulation of microtubule polymerization
GO:0031503 IEA protein complex localization
GO:0032767 IEA copper-dependent protein binding
GO:0035259 IEA glucocorticoid receptor binding
GO:0043005 IEA neuron projection
GO:0043025 IEA neuronal cell body
GO:0043234 IEA protein complex
GO:0044295 ISS axonal growth cone
GO:0044822 IDA poly(A) RNA binding
GO:0046661 IEA male sex differentiation
GO:0048156 IEA tau protein binding
GO:0048471 IEA perinuclear region of cytoplasm
GO:0048608 IEA reproductive structure development
GO:0051219 IEA phosphoprotein binding
GO:0061077 IDA chaperone-mediated protein folding
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008447 fkbp4 FK506 binding protein 4 protein_coding Danio_rerio
ENSMUSG00000030357 Fkbp4 FK506 binding protein 4 protein_coding Mus_musculus

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