C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase, cAMP-dependent, regulatory, type II, beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000005249 PRKAR2B 9606 + 7:107044649-107161811 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265717 PRKAR2B-001 107044649-107161811 protein_coding
  ENST00000393613 PRKAR2B-003 107069625-107140953 processed_transcript
  ENST00000488792 PRKAR2B-004 107091676-107146462 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000265717
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000265717 37.716±0.00 2.692±0.00 0.954±0.00 13.487±5.15 56.208±51.23 4.197±0.33 4.067±1.57 3.057±2.89 4.419±3.49 3.079±1.84 0.306±0.05 7.315±6.08 9.200±2.90 13.304±0.20

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000086 TAS G2/M transition of mitotic cell cycle
GO:0000278 TAS mitotic cell cycle
GO:0001932 IEA regulation of protein phosphorylation
GO:0004862 IDA cAMP-dependent protein kinase inhibitor activity
GO:0005515 IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005813 IDA centrosome
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0005952 IEA cAMP-dependent protein kinase complex
GO:0006112 TAS energy reserve metabolic process
GO:0006631 IEA fatty acid metabolic process
GO:0006833 TAS water transport
GO:0007165 TAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007202 TAS activation of phospholipase C activity
GO:0007596 TAS blood coagulation
GO:0007612 IEA learning
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0008603 IDA:IEA cAMP-dependent protein kinase regulator activity
GO:0019901 IEA protein kinase binding
GO:0030552 IEA cAMP binding
GO:0031625 IDA ubiquitin protein ligase binding
GO:0034199 TAS activation of protein kinase A activity
GO:0034236 IPI protein kinase A catalytic subunit binding
GO:0035556 TAS intracellular signal transduction
GO:0043197 ISS dendritic spine
GO:0043198 ISS dendritic shaft
GO:0044281 TAS small molecule metabolic process
GO:0045087 TAS innate immune response
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0050796 TAS regulation of insulin secretion
GO:0055085 TAS transmembrane transport
GO:0070062 IDA extracellular vesicular exosome
GO:0071377 TAS cellular response to glucagon stimulus
GO:0097546 IEA ciliary base
GO:2000480 IDA negative regulation of cAMP-dependent protein kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036446 PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta protein_coding Danio_rerio
ENSMUSG00000002997 Prkar2b protein kinase, cAMP dependent regulatory, type II beta protein_coding Mus_musculus

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