C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: F-box and leucine-rich repeat protein 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000005812 FBXL3 9606 - 13:76992598-77027195 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000355619 FBXL3-001 77005254-77027150 protein_coding
  ENST00000417323 FBXL3-002 77007565-77027195 protein_coding
  ENST00000470210 FBXL3-005 77015165-77018744 processed_transcript
  ENST00000472949 FBXL3-003 77015511-77027085 processed_transcript
  ENST00000477982 FBXL3-006 76999137-77018686 processed_transcript
  ENST00000485797 FBXL3-004 76992598-77015581 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000355619ENST00000417323ENST00000477982
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000355619 15.484±0.00 15.273±0.00 2.016±0.00 9.390±4.21 8.463±4.41 8.184±3.65 4.028±1.82 7.500±5.43 4.615±0.37 8.511±0.59 4.176±3.30 7.396±3.57 7.312±1.32 15.794±6.28
ENST00000417323 N/A N/A N/A N/A N/A N/A N/A 7.601±0.00 8.487±0.00 N/A N/A N/A N/A N/A
ENST00000477982 5.775±0.00 N/A 2.362±0.00 2.005±0.00 N/A 5.367±0.00 2.405±1.13 7.576±5.17 4.194±0.00 4.157±1.37 1.257±0.69 4.955±1.45 7.143±1.45 6.496±2.25

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00004A CIL_00004A_0001 CGP 13:76948497-77002517
CIL_0004PQ CIL_0004PQ_0002 CGP 13:76990660-77027195
CIL_00004B CIL_00004B_0001 CGP 13:76992598-77327050

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000151 NAS ubiquitin ligase complex
GO:0004842 NAS ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 ISS nucleus
GO:0005829 ISS cytosol
GO:0016567 ISS protein ubiquitination
GO:0019005 IDA SCF ubiquitin ligase complex
GO:0031146 IDA SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031648 ISS protein destabilization
GO:0042752 IMP regulation of circadian rhythm
GO:0043153 ISS entrainment of circadian clock by photoperiod
GO:0043161 IEA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0048511 IEA rhythmic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021882 fbxl3b F-box and leucine-rich repeat protein 3b protein_coding Danio_rerio
ENSDARG00000078003 fbxl3a F-box and leucine-rich repeat protein 3a protein_coding Danio_rerio
ENSMUSG00000022124 Fbxl3 F-box and leucine-rich repeat protein 3 protein_coding Mus_musculus

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