C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: megakaryocyte-associated tyrosine kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000007264 MATK 9606 - 19:3777970-3802129 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000310132 MATK-003 3777973-3786416 protein_coding
  ENST00000395040 MATK-002 3777973-3786413 protein_coding
  ENST00000395045 MATK-001 3777975-3801812 protein_coding
  ENST00000585778 MATK-004 3777975-3786282 protein_coding
  ENST00000587180 MATK-008 3779789-3784573 protein_coding
  ENST00000588983 MATK-009 3779389-3783918 protein_coding
  ENST00000590028 MATK-006 3783872-3786073 protein_coding
  ENST00000590493 MATK-010 3779133-3784152 protein_coding
  ENST00000590821 MATK-014 3787460-3801802 processed_transcript
  ENST00000590849 MATK-005 3784021-3801799 protein_coding
  ENST00000590980 MATK-011 3785247-3802129 protein_coding
  ENST00000591059 MATK-007 3785097-3786016 protein_coding
  ENST00000592300 MATK-012 3793130-3801803 processed_transcript
  ENST00000592612 MATK-013 3793074-3801781 processed_transcript
  ENST00000612526 MATK-201 3777975-3786282 protein_coding
  ENST00000619596 MATK-202 3777970-3789347 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000310132ENST00000395040ENST00000395045ENST00000585778ENST00000587180ENST00000588983ENST00000590028ENST00000590493ENST00000591059ENST00000592300ENST00000619596
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000310132 N/A N/A N/A 3.577±0.00 0.468±0.00 N/A N/A 0.293±0.00 N/A 1.627±0.00 N/A N/A N/A N/A
ENST00000395040 N/A 1.060±0.00 N/A 2.529±0.64 N/A 0.471±0.00 N/A 0.206±0.00 N/A 1.020±0.00 N/A 0.330±0.00 N/A N/A
ENST00000395045 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.516±0.00 N/A N/A
ENST00000585778 N/A N/A N/A N/A N/A 0.289±0.00 0.037±0.00 N/A N/A N/A N/A 0.103±0.00 N/A 0.918±0.00
ENST00000587180 N/A N/A 0.808±0.00 5.225±0.00 N/A 3.173±0.00 0.138±0.00 N/A 1.476±0.00 N/A 0.291±0.16 0.739±0.38 1.313±0.00 1.936±0.00
ENST00000588983 N/A N/A N/A N/A N/A 0.414±0.00 N/A N/A N/A N/A 0.472±0.00 N/A N/A N/A
ENST00000590028 N/A N/A N/A N/A N/A N/A 0.346±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000590493 0.225±0.00 1.838±0.00 N/A 6.534±3.95 N/A N/A N/A 0.089±0.00 N/A 1.889±0.00 N/A 0.486±0.31 N/A 2.129±0.00
ENST00000591059 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.269±0.00 N/A N/A
ENST00000592300 0.211±0.00 N/A N/A N/A N/A N/A 0.138±0.00 0.511±0.00 N/A N/A N/A N/A N/A N/A
ENST00000619596 N/A 1.646±0.00 N/A 5.076±0.00 2.547±0.00 0.126±0.00 N/A 0.389±0.00 0.246±0.00 3.775±0.00 N/A N/A 0.213±0.00 0.578±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005QR CIL_0005QR_0002 CGP 19:3777970-3869032

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004713 TAS:IEA protein tyrosine kinase activity
GO:0004715 IEA non-membrane spanning protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005829 TAS cytosol
GO:0006468 TAS:IEA protein phosphorylation
GO:0007498 TAS mesoderm development
GO:0008283 TAS cell proliferation
GO:0008284 TAS positive regulation of cell proliferation
GO:0016020 IEA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074670 matk megakaryocyte-associated tyrosine kinase protein_coding Danio_rerio
ENSMUSG00000004933 Matk megakaryocyte-associated tyrosine kinase protein_coding Mus_musculus

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