C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ADAM metallopeptidase domain 22
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000008277 ADAM22 9606 + 7:87934143-88202889 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265727 ADAM22-001 87934387-88196582 protein_coding
  ENST00000398201 ADAM22-004 87934347-88182113 protein_coding
  ENST00000398203 ADAM22-008 87934756-88181608 protein_coding
  ENST00000398204 ADAM22-003 87934143-88202889 protein_coding
  ENST00000398209 ADAM22-002 87934420-88202889 protein_coding
  ENST00000412441 ADAM22-009 87934329-88114648 protein_coding
  ENST00000413139 ADAM22-006 88165858-88196491 protein_coding
  ENST00000426930 ADAM22-005 88163031-88196757 protein_coding
  ENST00000439864 ADAM22-007 87934251-88132804 protein_coding
  ENST00000476330 ADAM22-012 88182005-88186422 processed_transcript
  ENST00000478920 ADAM22-010 88089919-88130439 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000265727ENST00000398201ENST00000398203ENST00000398204ENST00000398209ENST00000426930ENST00000439864ENST00000478920
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000265727 0.135±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.066±0.03 N/A
ENST00000398201 N/A N/A 7.207±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000398203 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.046±0.00 0.508±0.00 0.233±0.00 N/A
ENST00000398204 N/A 0.972±0.00 8.824±3.18 0.259±0.00 0.287±0.00 0.162±0.00 0.741±0.00 0.301±0.30 0.526±0.00 0.307±0.00 0.694±0.36 0.096±0.00 0.531±0.17
ENST00000398209 N/A 0.655±0.00 1.481±0.00 0.278±0.00 N/A 0.084±0.00 N/A N/A N/A N/A 0.322±0.15 N/A N/A
ENST00000426930 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.133±0.00 N/A N/A N/A
ENST00000439864 N/A N/A N/A N/A 0.737±0.00 0.172±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000478920 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.205±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004SX CIL_0004SX_0002 CGP 7:87876216-88202889

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004222 IEA metalloendopeptidase activity
GO:0005178 NAS integrin binding
GO:0005515 IPI protein binding
GO:0006508 IEA proteolysis
GO:0007155 IEA cell adhesion
GO:0007162 NAS negative regulation of cell adhesion
GO:0007417 TAS central nervous system development
GO:0008270 IEA zinc ion binding
GO:0008344 IEA adult locomotory behavior
GO:0014037 IEA Schwann cell differentiation
GO:0016021 NAS integral component of membrane
GO:0022011 IEA myelination in peripheral nervous system
GO:0042063 IEA gliogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060532 adam22 a disintegrin and metallopeptidase domain 22 protein_coding Danio_rerio
ENSMUSG00000040537 Adam22 a disintegrin and metallopeptidase domain 22 protein_coding Mus_musculus

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