C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: microsomal glutathione S-transferase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000008394 MGST1 9606 + 12:16347142-16609259 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000010404 MGST1-201 16347142-16364409 protein_coding
  ENST00000359720 MGST1-016 16382827-16438761 processed_transcript
  ENST00000396207 MGST1-002 16353417-16364409 protein_coding
  ENST00000396209 MGST1-202 16347778-16364409 protein_coding
  ENST00000396210 MGST1-001 16347649-16364403 protein_coding
  ENST00000534835 MGST1-008 16347645-16349106 processed_transcript
  ENST00000535309 MGST1-004 16347694-16377192 protein_coding
  ENST00000535624 MGST1-011 16357511-16364260 retained_intron
  ENST00000536371 MGST1-005 16347142-16363806 protein_coding
  ENST00000537878 MGST1-012 16347654-16354724 retained_intron
  ENST00000538857 MGST1-015 16354231-16589580 processed_transcript
  ENST00000538885 MGST1-009 16350746-16354378 protein_coding
  ENST00000539036 MGST1-017 16347652-16609259 processed_transcript
  ENST00000539708 MGST1-010 16347664-16364060 processed_transcript
  ENST00000540056 MGST1-007 16347778-16364071 protein_coding
  ENST00000540126 MGST1-006 16347797-16363814 protein_coding
  ENST00000542256 MGST1-003 16347654-16370408 processed_transcript
  ENST00000543076 MGST1-013 16347645-16363999 protein_coding
  ENST00000624056 MGST1-014 16362568-16364409 TEC

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000010404ENST00000396207ENST00000396209ENST00000396210ENST00000535624ENST00000538857ENST00000539036ENST00000543076ENST00000624056
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000010404 N/A N/A N/A N/A 10.515±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 6.407±0.00
ENST00000396207 N/A 2.222±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000396209 N/A N/A 1.535±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000396210 205.998±0.00 8.911±0.00 3.465±0.00 13.276±4.92 205.840±199.13 43.923±10.95 7.756±5.04 114.742±31.91 195.214±174.11 50.162±0.00 8.301±0.00 32.178±23.38 12.098±2.97 7.436±5.50
ENST00000535624 N/A N/A 5.795±0.00 N/A N/A 13.187±0.00 3.102±2.11 44.935±0.00 150.685±0.00 N/A 3.189±0.64 86.807±0.00 13.195±0.00 3.534±0.00
ENST00000538857 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.422±0.00
ENST00000539036 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.242±0.00 N/A N/A N/A
ENST00000543076 239.702±0.00 14.639±0.00 N/A 28.235±0.00 574.618±0.00 74.448±0.00 N/A N/A N/A N/A N/A 153.007±0.00 24.684±0.00 4.699±0.00
ENST00000624056 N/A N/A 0.528±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007NM CIL_0007NM_0001 UCNEbase 12:16018180-18077080
CIL_00098O CIL_00098O_0001 VISTA 12:16157111-16759002
CIL_0005FD CIL_0005FD_0001 CGP 12:16188485-16609259
CIL_0009BE CIL_0009BE_0001 VISTA 12:16262381-16863426
CIL_0005FE CIL_0005FE_0001 CGP 12:16347142-16610594

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004364 IDA glutathione transferase activity
GO:0004602 IDA glutathione peroxidase activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005739 IDA mitochondrion
GO:0005741 IEA mitochondrial outer membrane
GO:0005743 IEA mitochondrial inner membrane
GO:0005778 ISS peroxisomal membrane
GO:0005783 ISS endoplasmic reticulum
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006749 IEA glutathione metabolic process
GO:0006805 TAS xenobiotic metabolic process
GO:0010243 IEA response to organonitrogen compound
GO:0016021 ISS integral component of membrane
GO:0032496 IEA response to lipopolysaccharide
GO:0033327 IEA Leydig cell differentiation
GO:0042493 IEA response to drug
GO:0042802 IEA identical protein binding
GO:0042803 IEA protein homodimerization activity
GO:0043295 IEA glutathione binding
GO:0044281 TAS small molecule metabolic process
GO:0045177 IEA apical part of cell
GO:0055114 IDA oxidation-reduction process
GO:0070207 ISS protein homotrimerization
GO:0071449 IDA cellular response to lipid hydroperoxide
GO:1901687 TAS glutathione derivative biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000022165 mgst1.2 microsomal glutathione S-transferase 1.2 protein_coding Danio_rerio
ENSDARG00000032618 mgst1.1 microsomal glutathione S-transferase 1.1 protein_coding Danio_rerio
ENSMUSG00000008540 Mgst1 microsomal glutathione S-transferase 1 protein_coding Mus_musculus

Loading