C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mitogen-activated protein kinase 8 interacting protein 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000008735 MAPK8IP2 9606 + 22:50600685-50613981 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000008876 MAPK8IP2-002 50603133-50613981 protein_coding
  ENST00000329492 MAPK8IP2-001 50600685-50611551 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000008876ENST00000329492
Transcript ID Adipose Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000008876 0.069±0.00 13.265±0.00 0.100±0.05 0.174±0.15 N/A 0.096±0.00 0.052±0.00 N/A N/A 1.036±0.00 0.266±0.00 0.847±0.00
ENST00000329492 1.233±0.00 43.592±30.23 1.065±0.00 1.198±1.05 0.152±0.07 0.901±0.85 0.056±0.00 0.535±0.00 0.178±0.00 5.848±6.89 2.190±0.79 5.113±0.44

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002NX CIL_0002NX_0001 CGP 22:50600685-50628173

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000165 IDA MAPK cascade
GO:0001540 NAS beta-amyloid binding
GO:0001662 ISS behavioral fear response
GO:0005078 NAS MAP-kinase scaffold activity
GO:0005198 TAS structural molecule activity
GO:0005515 IPI:IEA protein binding
GO:0005737 IDA cytoplasm
GO:0007172 TAS signal complex assembly
GO:0007254 IEA JNK cascade
GO:0007617 IEA mating behavior
GO:0009967 NAS positive regulation of signal transduction
GO:0010469 ISS regulation of receptor activity
GO:0019894 ISS kinesin binding
GO:0019901 IPI protein kinase binding
GO:0030295 IDA protein kinase activator activity
GO:0032403 IEA protein complex binding
GO:0032874 IEA positive regulation of stress-activated MAPK cascade
GO:0035176 ISS social behavior
GO:0043025 IEA neuronal cell body
GO:0043234 IEA protein complex
GO:0045860 IDA positive regulation of protein kinase activity
GO:0046328 IDA regulation of JNK cascade
GO:0046958 ISS nonassociative learning
GO:0048813 ISS dendrite morphogenesis
GO:0051966 ISS regulation of synaptic transmission, glutamatergic
GO:0060079 ISS regulation of excitatory postsynaptic membrane potential
GO:0097481 ISS neuronal postsynaptic density
GO:2000310 ISS regulation of N-methyl-D-aspartate selective glutamate receptor activity
GO:2000311 ISS regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063157 mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 protein_coding Danio_rerio
ENSMUSG00000022619 Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 protein_coding Mus_musculus

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