C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: MLX interacting protein-like
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000009950 MLXIPL 9606 - 7:73593194-73624543 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000313375 MLXIPL-001 73593194-73624540 protein_coding
  ENST00000345114 MLXIPL-004 73593194-73624492 nonsense_mediated_decay
  ENST00000354613 MLXIPL-002 73593194-73624540 protein_coding
  ENST00000414749 MLXIPL-010 73593194-73624492 protein_coding
  ENST00000429400 MLXIPL-011 73593194-73624492 protein_coding
  ENST00000434326 MLXIPL-003 73593202-73624514 protein_coding
  ENST00000453275 MLXIPL-006 73597645-73624543 protein_coding
  ENST00000456640 MLXIPL-007 73605910-73616161 protein_coding
  ENST00000467221 MLXIPL-009 73596174-73597362 retained_intron
  ENST00000476404 MLXIPL-005 73596710-73606824 retained_intron
  ENST00000488212 MLXIPL-008 73599592-73607120 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000313375ENST00000345114ENST00000354613ENST00000414749ENST00000429400ENST00000434326ENST00000453275ENST00000456640ENST00000467221ENST00000476404ENST00000488212
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000313375 N/A N/A N/A N/A N/A N/A N/A 26.492±0.00 N/A 2.063±0.00 2.307±0.00 N/A N/A
ENST00000345114 N/A N/A N/A N/A N/A N/A N/A 8.200±0.00 0.141±0.00 1.710±0.00 N/A 0.025±0.00 N/A
ENST00000354613 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.024±0.00 N/A
ENST00000414749 N/A N/A N/A N/A N/A N/A 1.977±0.00 0.582±0.00 N/A N/A N/A N/A N/A
ENST00000429400 N/A N/A N/A 8.162±0.00 N/A N/A 5.874±0.00 N/A N/A N/A 1.646±1.79 N/A 4.242±2.14
ENST00000434326 2.792±0.00 N/A 0.057±0.00 5.569±0.00 N/A N/A 1.305±0.00 12.495±0.00 N/A 0.892±0.00 1.181±0.38 N/A 1.454±0.43
ENST00000453275 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.109±0.00 N/A
ENST00000456640 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.141±0.00 N/A
ENST00000467221 N/A N/A N/A N/A 1.001±0.00 N/A N/A N/A N/A N/A 4.886±0.00 N/A N/A
ENST00000476404 N/A 0.209±0.00 N/A N/A N/A 0.042±0.03 N/A 0.086±0.00 0.083±0.00 N/A 0.172±0.00 0.047±0.00 N/A
ENST00000488212 N/A N/A N/A N/A N/A N/A 5.650±0.00 N/A N/A N/A 0.926±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0003677 NAS DNA binding
GO:0003700 NAS sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 NAS nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 NAS transcription factor complex
GO:0005737 ISS cytoplasm
GO:0005829 TAS cytosol
GO:0006112 TAS energy reserve metabolic process
GO:0006351 IEA transcription, DNA-templated
GO:0006355 NAS regulation of transcription, DNA-templated
GO:0008134 IPI transcription factor binding
GO:0008284 IMP positive regulation of cell proliferation
GO:0009653 TAS anatomical structure morphogenesis
GO:0010255 ISS glucose mediated signaling pathway
GO:0031325 TAS positive regulation of cellular metabolic process
GO:0033137 IMP negative regulation of peptidyl-serine phosphorylation
GO:0035538 TAS carbohydrate response element binding
GO:0035556 TAS intracellular signal transduction
GO:0042304 TAS regulation of fatty acid biosynthetic process
GO:0042593 ISS glucose homeostasis
GO:0044281 TAS small molecule metabolic process
GO:0045723 ISS positive regulation of fatty acid biosynthetic process
GO:0045821 IMP positive regulation of glycolytic process
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0046889 IMP positive regulation of lipid biosynthetic process
GO:0046982 IPI protein heterodimerization activity
GO:0046983 IEA protein dimerization activity
GO:0055089 ISS fatty acid homeostasis
GO:0070328 NAS triglyceride homeostasis
GO:0071157 IMP negative regulation of cell cycle arrest
GO:0090324 IMP negative regulation of oxidative phosphorylation
GO:2000505 ISS regulation of energy homeostasis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000089107 MLXIPL MLX interacting protein-like protein_coding Danio_rerio
ENSMUSG00000005373 Mlxipl MLX interacting protein-like protein_coding Mus_musculus

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