C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NME/NM23 nucleoside diphosphate kinase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000011052 NME2 9606 + 17:51153590-51171744 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000376392 NME2-003 51153604-51171744 protein_coding
  ENST00000393193 NME2-001 51153590-51171744 protein_coding
  ENST00000555572 NME2-002 51153636-51171742 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastLiverLungENST00000393193
Transcript ID Adrenal Brain Breast Liver Lung
ENST00000393193 61.651±0.00 23.574±9.11 43.438±0.00 38.181±0.00 28.752±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000977 IEA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001726 IDA ruffle
GO:0002762 IEA negative regulation of myeloid leukocyte differentiation
GO:0003677 IEA DNA binding
GO:0003697 IEA single-stranded DNA binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0004550 IEA nucleoside diphosphate kinase activity
GO:0004673 IEA protein histidine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005813 IEA centrosome
GO:0005829 TAS cytosol
GO:0005882 IEA intermediate filament
GO:0006165 IEA nucleoside diphosphate phosphorylation
GO:0006183 IEA GTP biosynthetic process
GO:0006228 IEA UTP biosynthetic process
GO:0006241 IEA CTP biosynthetic process
GO:0006351 IEA transcription, DNA-templated
GO:0006355 TAS regulation of transcription, DNA-templated
GO:0007155 TAS cell adhesion
GO:0007229 IDA integrin-mediated signaling pathway
GO:0009142 IDA nucleoside triphosphate biosynthetic process
GO:0010629 IEA negative regulation of gene expression
GO:0010976 IEA positive regulation of neuron projection development
GO:0014075 IEA response to amine
GO:0015949 TAS nucleobase-containing small molecule interconversion
GO:0016020 IEA membrane
GO:0018106 IEA peptidyl-histidine phosphorylation
GO:0019215 IEA intermediate filament binding
GO:0019899 IEA enzyme binding
GO:0019901 IEA protein kinase binding
GO:0021766 IEA hippocampus development
GO:0030027 IDA lamellipodium
GO:0033574 IEA response to testosterone
GO:0035690 IEA cellular response to drug
GO:0042493 IEA response to drug
GO:0043015 IEA gamma-tubulin binding
GO:0043066 IMP negative regulation of apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0045618 IMP positive regulation of keratinocyte differentiation
GO:0045682 IMP regulation of epidermis development
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0048471 IEA perinuclear region of cytoplasm
GO:0050679 IMP positive regulation of epithelial cell proliferation
GO:0051591 IEA response to cAMP
GO:0055086 TAS nucleobase-containing small molecule metabolic process
GO:0070062 IDA extracellular vesicular exosome
GO:0071333 IEA cellular response to glucose stimulus
GO:0071398 IEA cellular response to fatty acid
GO:0071944 IDA cell periphery

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076892 nme2b.2 NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 2 protein_coding Danio_rerio
ENSMUSG00000037601 Nme1 NME/NM23 nucleoside diphosphate kinase 1 protein_coding Mus_musculus
ENSMUSG00000091228 Gm20390 predicted gene 20390 protein_coding Mus_musculus

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