C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: membrane-bound transcription factor peptidase, site 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000012174 MBTPS2 9606 + X:21839636-21885424 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000365779 MBTPS2-002 21839654-21873084 protein_coding
  ENST00000379484 MBTPS2-001 21839636-21885424 protein_coding
  ENST00000465888 MBTPS2-003 21839636-21857593 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000365779ENST00000379484
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000365779 N/A N/A 0.753±0.00 N/A 0.385±0.00 N/A N/A N/A 0.282±0.00 0.457±0.00 N/A N/A N/A N/A
ENST00000379484 3.644±0.00 3.675±0.00 1.530±0.00 5.059±0.00 2.383±0.77 2.332±0.56 1.723±1.33 3.508±0.09 2.251±0.80 1.529±0.18 1.895±0.83 3.671±1.18 3.844±0.42 2.496±1.18

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002L6 CIL_0002L6_0002 CGP X:21705972-21885424
CIL_0005Z6 CIL_0005Z6_0001 CGP X:21839636-21885424

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 TAS Golgi membrane
GO:0004222 IEA metalloendopeptidase activity
GO:0005515 IEA protein binding
GO:0005737 IDA cytoplasm
GO:0006508 IEA proteolysis
GO:0006987 TAS activation of signaling protein activity involved in unfolded protein response
GO:0008203 IEA cholesterol metabolic process
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030968 TAS endoplasmic reticulum unfolded protein response
GO:0044267 TAS cellular protein metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057577 mbtps2 membrane-bound transcription factor protease, site 2 protein_coding Danio_rerio
ENSMUSG00000046873 Mbtps2 membrane-bound transcription factor peptidase, site 2 protein_coding Mus_musculus

Loading