C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dipeptidase 1 (renal)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000015413 DPEP1 9606 + 16:89613308-89638456 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261615 DPEP1-001 89630289-89638456 protein_coding
  ENST00000393092 DPEP1-002 89620592-89638429 protein_coding
  ENST00000421184 DPEP1-201 89613308-89638430 protein_coding
  ENST00000561484 DPEP1-006 89626458-89636179 retained_intron
  ENST00000564281 DPEP1-003 89613673-89638398 retained_intron
  ENST00000564645 DPEP1-007 89637576-89638295 retained_intron
  ENST00000565249 DPEP1-004 89613549-89637529 retained_intron
  ENST00000568281 DPEP1-008 89616873-89636360 protein_coding
  ENST00000570029 DPEP1-005 89613308-89636348 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000261615ENST00000393092ENST00000561484ENST00000564281ENST00000564645ENST00000565249ENST00000568281
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000261615 0.263±0.00 N/A 8.224±0.00 N/A 0.281±0.08 N/A N/A 53.949±0.00 0.020±0.00 0.348±0.00 18.580±16.57 N/A 47.950±0.00
ENST00000393092 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.451±0.00 N/A 0.591±0.57 20.808±3.75
ENST00000561484 N/A N/A N/A N/A 0.615±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000564281 N/A N/A N/A N/A N/A 0.125±0.00 N/A N/A N/A N/A 8.374±4.72 N/A 6.353±0.00
ENST00000564645 N/A 0.619±0.00 N/A N/A N/A 0.332±0.00 0.054±0.00 43.548±0.00 0.044±0.00 N/A 18.239±16.31 N/A N/A
ENST00000565249 N/A N/A N/A 0.034±0.00 0.076±0.00 N/A N/A N/A N/A N/A N/A 0.061±0.00 N/A
ENST00000568281 N/A N/A 16.704±0.00 N/A N/A N/A N/A N/A N/A 1.372±0.00 3.241±0.00 0.274±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008HA CIL_0008HA_0001 VISTA 16:89018329-89621235
CIL_000334 CIL_000334_0001 CGP 16:89613308-89657845

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005615 ISS extracellular space
GO:0005886 IDA plasma membrane
GO:0006508 IEA proteolysis
GO:0006691 TAS leukotriene metabolic process
GO:0006749 TAS glutathione metabolic process
GO:0008235 TAS metalloexopeptidase activity
GO:0008237 IEA metallopeptidase activity
GO:0008239 IEA dipeptidyl-peptidase activity
GO:0008270 IDA zinc ion binding
GO:0016805 IEA dipeptidase activity
GO:0016999 IDA antibiotic metabolic process
GO:0019369 TAS arachidonic acid metabolic process
GO:0030336 IMP negative regulation of cell migration
GO:0031225 IEA anchored component of membrane
GO:0034235 ISS GPI anchor binding
GO:0035690 IDA cellular response to drug
GO:0042995 IEA cell projection
GO:0043027 IMP cysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0043066 IMP negative regulation of apoptotic process
GO:0043154 IMP negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0045177 IDA apical part of cell
GO:0046872 IEA metal ion binding
GO:0050667 IDA homocysteine metabolic process
GO:0070062 IDA extracellular vesicular exosome
GO:0070573 IDA metallodipeptidase activity
GO:0071277 ISS cellular response to calcium ion
GO:0071732 ISS cellular response to nitric oxide
GO:0072340 TAS cellular lactam catabolic process
GO:0072341 IDA modified amino acid binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000068181 dpep1 dipeptidase 1 (renal) protein_coding Danio_rerio
ENSMUSG00000019278 Dpep1 dipeptidase 1 (renal) protein_coding Mus_musculus

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