C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: macrophage receptor with collagenous structure
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000019169 MARCO 9606 + 2:118942166-118994660 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000327097 MARCO-001 118942166-118994660 protein_coding
  ENST00000412481 MARCO-003 118942290-118970339 protein_coding
  ENST00000494979 MARCO-004 118993017-118994658 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000327097ENST00000494979
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000327097 14.731±0.00 12.351±0.00 0.023±0.00 0.373±0.28 5.822±5.38 1.403±1.13 2.632±2.60 5.926±3.49 14.079±13.15 37.759±30.30 2.178±0.00 2.643±2.42 6.055±2.97 2.591±1.70
ENST00000494979 12.947±0.00 20.264±0.00 N/A 0.452±0.00 7.056±6.34 3.075±1.75 1.534±1.50 2.251±0.00 21.251±0.00 N/A 1.137±0.00 0.201±0.00 N/A 6.023±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002WW CIL_0002WW_0002 CGP 2:118842171-118994660
CIL_0002WR CIL_0002WR_0002 CGP 2:118942166-119158889

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002221 TAS pattern recognition receptor signaling pathway
GO:0004888 TAS transmembrane signaling receptor activity
GO:0005044 IEA scavenger receptor activity
GO:0005581 IEA collagen trimer
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006897 IEA endocytosis
GO:0006898 IEA receptor-mediated endocytosis
GO:0007166 TAS cell surface receptor signaling pathway
GO:0008329 TAS signaling pattern recognition receptor activity
GO:0016020 IEA membrane
GO:0030666 TAS endocytic vesicle membrane
GO:0043277 IEA apoptotic cell clearance
GO:0045087 IEA innate immune response

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059294 marco macrophage receptor with collagenous structure protein_coding Danio_rerio
ENSMUSG00000026390 Marco macrophage receptor with collagenous structure protein_coding Mus_musculus

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