C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serpin peptidase inhibitor, clade B (ovalbumin), member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000021355 SERPINB1 9606 - 6:2832332-2842006 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000380739 SERPINB1-003 2832332-2842006 protein_coding
  ENST00000460260 SERPINB1-001 2838549-2841862 processed_transcript
  ENST00000468511 SERPINB1-002 2833512-2837999 processed_transcript
  ENST00000476896 SERPINB1-004 2836108-2841848 processed_transcript
  ENST00000490094 SERPINB1-005 2835856-2841959 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000380739ENST00000468511ENST00000476896ENST00000490094
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000380739 12.328±0.00 48.552±0.00 4.852±3.38 10.557±4.77 9.060±2.98 4.506±2.71 8.813±5.73 10.819±7.33 47.238±41.10 7.420±0.00 23.320±15.72 18.860±3.46 4.854±1.87
ENST00000468511 N/A N/A 2.037±0.00 18.882±0.00 N/A N/A N/A N/A 15.788±0.00 N/A N/A N/A N/A
ENST00000476896 N/A N/A N/A N/A N/A N/A N/A N/A 6.366±0.00 N/A N/A N/A N/A
ENST00000490094 11.475±0.00 N/A 6.079±0.00 N/A 4.841±0.00 6.346±0.00 1.391±0.00 N/A 106.716±0.00 N/A 47.073±36.14 17.738±5.65 3.150±1.10

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00038D CIL_00038D_0001 CGP 6:2832332-2903280

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004867 IBA serine-type endopeptidase inhibitor activity
GO:0005615 IDA extracellular space
GO:0005737 IEA cytoplasm
GO:0010951 IBA negative regulation of endopeptidase activity
GO:0016020 IDA membrane
GO:0030162 IBA regulation of proteolysis
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055416 serpinb1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 protein_coding Danio_rerio
ENSDARG00000070396 serpinb1l2 serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 2 protein_coding Danio_rerio
ENSMUSG00000044734 Serpinb1a serine (or cysteine) peptidase inhibitor, clade B, member 1a protein_coding Mus_musculus
ENSMUSG00000051029 Serpinb1b serine (or cysteine) peptidase inhibitor, clade B, member 1b protein_coding Mus_musculus
ENSMUSG00000079049 Serpinb1c serine (or cysteine) peptidase inhibitor, clade B, member 1c protein_coding Mus_musculus

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