C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome P450, family 3, subfamily A, polypeptide 43
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000021461 CYP3A43 9606 + 7:99828013-99866102 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000222382 CYP3A43-014 99828116-99866001 protein_coding
  ENST00000312017 CYP3A43-013 99828116-99866001 protein_coding
  ENST00000342499 CYP3A43-201 99828013-99866102 protein_coding
  ENST00000354829 CYP3A43-001 99828013-99866095 protein_coding
  ENST00000415413 CYP3A43-006 99828049-99866045 protein_coding
  ENST00000417625 CYP3A43-003 99828043-99866001 protein_coding
  ENST00000433277 CYP3A43-009 99828049-99866045 nonsense_mediated_decay
  ENST00000434806 CYP3A43-012 99828116-99866001 nonsense_mediated_decay
  ENST00000436834 CYP3A43-002 99828043-99866001 nonsense_mediated_decay
  ENST00000444905 CYP3A43-005 99828049-99866045 protein_coding
  ENST00000463915 CYP3A43-004 99828049-99866045 processed_transcript
  ENST00000472352 CYP3A43-015 99855488-99861840 retained_intron
  ENST00000477658 CYP3A43-007 99828049-99866045 processed_transcript
  ENST00000481362 CYP3A43-011 99828116-99866001 retained_intron
  ENST00000491648 CYP3A43-010 99828049-99866045 processed_transcript
  ENST00000495115 CYP3A43-008 99828049-99866045 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000222382ENST00000312017ENST00000342499ENST00000354829ENST00000415413ENST00000417625ENST00000433277ENST00000463915ENST00000472352ENST00000481362ENST00000495115
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000222382 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.115±0.00
ENST00000312017 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.073±0.00 N/A N/A N/A
ENST00000342499 N/A N/A N/A N/A N/A N/A N/A N/A 0.187±0.00 N/A 0.040±0.00 N/A N/A
ENST00000354829 N/A N/A N/A N/A N/A N/A N/A N/A 0.282±0.00 N/A N/A N/A N/A
ENST00000415413 N/A N/A N/A N/A N/A N/A N/A N/A 0.336±0.00 N/A N/A 0.050±0.00 0.280±0.00
ENST00000417625 0.015±0.00 N/A N/A N/A 0.020±0.00 0.019±0.00 0.018±0.00 0.010±0.00 N/A N/A 0.021±0.00 N/A N/A
ENST00000433277 N/A N/A N/A 0.031±0.00 N/A N/A N/A N/A 0.079±0.00 N/A N/A N/A N/A
ENST00000463915 N/A N/A N/A N/A N/A N/A N/A 0.151±0.00 N/A N/A N/A N/A N/A
ENST00000472352 N/A N/A N/A N/A 0.066±0.00 N/A 0.015±0.00 N/A N/A N/A N/A 0.015±0.00 N/A
ENST00000481362 0.036±0.00 0.052±0.00 0.080±0.00 N/A 0.045±0.00 N/A 0.012±0.00 0.013±0.00 0.104±0.00 0.028±0.00 0.015±0.00 N/A 0.069±0.00
ENST00000495115 N/A N/A N/A N/A 0.028±0.00 0.149±0.00 N/A N/A N/A N/A N/A 0.032±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008QI CIL_0008QI_0001 VISTA 7:99696610-100298804
CIL_0005LC CIL_0005LC_0005 CGP 7:99756960-99866102

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004497 ISS monooxygenase activity
GO:0005506 IEA iron ion binding
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006805 TAS xenobiotic metabolic process
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 IEA heme binding
GO:0044281 TAS small molecule metabolic process
GO:0055114 IEA oxidation-reduction process
GO:0070330 IEA aromatase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015575 cyp3c1 cytochrome P450, family 3, subfamily c, polypeptide 1 protein_coding Danio_rerio
ENSDARG00000037873 cyp3c1l2 cytochrome P450, family 3, subfamily c, polypeptide 1 like, 2 protein_coding Danio_rerio
ENSDARG00000037874 si:dkey-21n8.3 si:dkey-21n8.3 protein_coding Danio_rerio
ENSDARG00000045627 cyp3a65 cytochrome P450, family 3, subfamily A, polypeptide 65 protein_coding Danio_rerio
ENSDARG00000070021 cyp3c4 cytochrome P450, family 3, subfamily C, polypeptide 4 protein_coding Danio_rerio

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