C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: complement component 8, beta polypeptide
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000021852 C8B 9606 - 1:56929210-56966140 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000371237 C8B-001 56929210-56966015 protein_coding
  ENST00000465658 C8B-002 56931594-56933381 retained_intron
  ENST00000468990 C8B-003 56956855-56966057 processed_transcript
  ENST00000494324 C8B-004 56960063-56966140 processed_transcript
  ENST00000535057 C8B-201 56929212-56966140 protein_coding
  ENST00000543257 C8B-202 56929212-56966140 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; KidneyLiverLungENST00000371237
Transcript ID Kidney Liver Lung
ENST00000371237 62.349±0.00 296.847±0.00 2.416±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00005D CIL_00005D_0002 CGP 1:56854806-56966140
CIL_00005G CIL_00005G_0002 CGP 1:56929210-58546734

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005576 TAS extracellular region
GO:0005579 IEA membrane attack complex
GO:0005615 IEA extracellular space
GO:0006955 IEA:TAS immune response
GO:0006956 TAS complement activation
GO:0006957 IEA complement activation, alternative pathway
GO:0006958 IEA complement activation, classical pathway
GO:0016020 TAS membrane
GO:0019835 IEA cytolysis
GO:0030449 TAS regulation of complement activation
GO:0031982 IDA vesicle
GO:0032403 IEA protein complex binding
GO:0045087 TAS innate immune response
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039517 c8b complement component 8, beta polypeptide protein_coding Danio_rerio
ENSMUSG00000029656 C8b complement component 8, beta polypeptide protein_coding Mus_musculus

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