C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serine/threonine kinase receptor associated protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000023734 STRAP 9606 + 12:15882391-15903478 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000025399 STRAP-002 15882394-15903014 protein_coding
  ENST00000419869 STRAP-001 15882395-15903478 protein_coding
  ENST00000536737 STRAP-005 15895454-15898272 retained_intron
  ENST00000538718 STRAP-006 15897945-15903340 protein_coding
  ENST00000539887 STRAP-007 15900899-15903478 retained_intron
  ENST00000541731 STRAP-003 15882391-15903442 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000025399ENST00000419869ENST00000538718ENST00000539887ENST00000541731
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000025399 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 80.513±0.00 29.629±0.00 31.313±0.00
ENST00000419869 45.547±0.00 21.894±0.00 6.060±0.00 27.920±8.17 28.076±15.03 22.394±12.35 22.492±15.05 26.674±16.31 14.683±5.22 21.682±15.69 19.190±9.31 38.843±7.87 33.875±3.16 27.113±8.87
ENST00000538718 19.345±0.00 16.782±0.00 N/A 19.183±0.00 19.803±0.00 N/A N/A 20.010±0.00 10.549±0.00 N/A 18.638±0.00 39.359±0.00 N/A 27.987±0.00
ENST00000539887 N/A 19.112±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 22.726±0.00 N/A N/A
ENST00000541731 N/A N/A 0.833±0.00 N/A N/A 6.761±0.00 7.892±0.00 N/A N/A N/A N/A 11.456±5.64 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007F9 CIL_0007F9_0001 CGP 12:15620158-15903478
CIL_000896 CIL_000896_0001 VISTA 12:15717656-16318890
CIL_0005FF CIL_0005FF_0001 CGP 12:15882391-16037282

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000387 IDA spliceosomal snRNP assembly
GO:0005102 IEA receptor binding
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0005886 IDA plasma membrane
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0010633 IMP negative regulation of epithelial cell migration
GO:0010719 IMP negative regulation of epithelial to mesenchymal transition
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0030054 IDA cell junction
GO:0030277 IMP maintenance of gastrointestinal epithelium
GO:0030512 IMP negative regulation of transforming growth factor beta receptor signaling pathway
GO:0032797 IDA SMN complex
GO:0034719 IDA SMN-Sm protein complex
GO:0044822 IDA poly(A) RNA binding
GO:0050680 IMP negative regulation of epithelial cell proliferation
GO:0060394 IMP negative regulation of pathway-restricted SMAD protein phosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007405 strap serine/threonine kinase receptor associated protein protein_coding Danio_rerio
ENSMUSG00000030224 Strap serine/threonine kinase receptor associated protein protein_coding Mus_musculus

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