C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: death-associated protein kinase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000035664 DAPK2 9606 - 15:63907036-64072033 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000261891 DAPK2-201 63907036-64040267 protein_coding
  ENST00000457488 DAPK2-001 63907923-64046322 protein_coding
  ENST00000557867 DAPK2-010 63911852-63926201 retained_intron
  ENST00000558064 DAPK2-004 63909184-63911943 nonsense_mediated_decay
  ENST00000558069 DAPK2-202 63922735-64040267 protein_coding
  ENST00000558076 DAPK2-009 63924512-63926074 retained_intron
  ENST00000558482 DAPK2-008 63929551-64046436 processed_transcript
  ENST00000559007 DAPK2-002 63907036-64040267 nonsense_mediated_decay
  ENST00000559306 DAPK2-007 63983605-64072033 protein_coding
  ENST00000559731 DAPK2-011 63908253-63916592 processed_transcript
  ENST00000559897 DAPK2-006 63939293-64030020 processed_transcript
  ENST00000561162 DAPK2-005 63971524-64046381 nonsense_mediated_decay
  ENST00000612884 DAPK2-003 63916147-64046322 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000261891ENST00000457488ENST00000557867ENST00000558064ENST00000558069ENST00000558482ENST00000559007ENST00000559731ENST00000612884
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000261891 1.781±0.00 N/A N/A 1.045±0.00 N/A 0.626±0.00 1.869±0.00 0.271±0.00 0.074±0.00 N/A N/A 0.567±0.11 0.741±0.14 0.349±0.00
ENST00000457488 9.612±0.00 2.972±0.00 N/A 1.369±0.00 8.215±0.00 N/A 4.117±0.00 0.301±0.00 0.405±0.05 3.196±1.25 N/A 2.316±2.61 0.215±0.00 0.838±0.06
ENST00000557867 N/A N/A 0.744±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000558064 N/A N/A N/A N/A N/A N/A N/A 1.118±0.00 N/A N/A N/A N/A N/A N/A
ENST00000558069 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 11.556±0.00 N/A N/A N/A
ENST00000558482 N/A N/A 1.586±0.00 N/A 3.855±0.00 N/A N/A 0.863±0.00 1.212±0.00 5.761±0.00 N/A N/A N/A N/A
ENST00000559007 0.920±0.00 0.578±0.00 N/A N/A 0.462±0.00 0.342±0.15 1.179±0.00 0.099±0.00 N/A 0.620±0.00 N/A 0.216±0.00 0.048±0.00 0.198±0.00
ENST00000559731 N/A N/A N/A N/A 3.716±0.00 N/A N/A N/A 0.539±0.00 N/A N/A N/A 0.432±0.00 2.341±0.00
ENST00000612884 N/A N/A 0.030±0.00 0.121±0.00 0.519±0.21 0.531±0.00 0.275±0.00 0.013±0.00 N/A N/A 5.017±0.73 0.173±0.11 0.010±0.00 0.163±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00050A CIL_00050A_0002 CGP 15:63608618-64072033

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004672 IEA protein kinase activity
GO:0004674 TAS protein serine/threonine kinase activity
GO:0004683 IBA calmodulin-dependent protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005516 IDA calmodulin binding
GO:0005524 IEA:IDA ATP binding
GO:0005737 IDA cytoplasm
GO:0006468 IEA:IDA protein phosphorylation
GO:0006915 TAS apoptotic process
GO:0010506 TAS regulation of autophagy
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0031410 IEA cytoplasmic vesicle
GO:0035556 IDA intracellular signal transduction
GO:0042802 IPI identical protein binding
GO:0042981 TAS regulation of apoptotic process
GO:0043276 IMP anoikis
GO:0046777 TAS protein autophosphorylation
GO:2001242 IMP regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061096 dapk2 death-associated protein kinase 2 protein_coding Danio_rerio
ENSMUSG00000032380 Dapk2 death-associated protein kinase 2 protein_coding Mus_musculus

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